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Cuiting Lin

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Articles 10
Citations 64
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Recent Articles
1.
Yang Y, Lin C, Zheng Q, Zhang L, Li Y, Huang Q, et al.
Front Pharmacol . 2023 Feb; 14:1016633. PMID: 36817129
Hyperuricemia (HUA) is associated with left ventricular remodeling (LVR) and thereby causes the initiation and development of a large number of cardiovascular diseases. LVR is typically accompanied by cardiomyocyte energy...
2.
Zhao Z, Luo J, Liao H, Zheng F, Chen X, Luo J, et al.
Bioorg Chem . 2023 Feb; 133:106405. PMID: 36753966
Previously we discovered a novel natural scaffold compound, isobavachin (4', 7-dihydroxy-8-prenylflavanone), as a potent URAT1 inhibitor by shape and structure based on a virtue screening approach. In this study, further...
3.
Lin C, Zheng Q, Li Y, Wu T, Luo J, Jiang Y, et al.
Exp Biol Med (Maywood) . 2022 Sep; 248(2):165-174. PMID: 36112877
Cellular cytoplasmic xanthine oxidase (XO)-mediated uric acid synthesis and extracellular excess uric acid exposure are both causes of cardiomyocytic injury under the condition of hyperuricemia (HUA). Potassium oxonate suppresses uric...
4.
Zhao Z, Liu J, Yuan L, Yang Z, Kuang P, Liao H, et al.
Eur J Med Chem . 2022 Aug; 242:114682. PMID: 36001935
Benzbromarone (BM) is a potent URAT1 inhibitor approved for the treatment of gout. However, the low URAT1-selectivity and hepatotoxcity limit its clinical use. To solve these problems, we rationally designed...
5.
Cai J, Lin C, Lai S, Liu Y, Liang M, Qin Y, et al.
Lipids Health Dis . 2021 Oct; 20(1):145. PMID: 34706716
Background: Non-alcoholic fatty liver disease (NAFLD) has been entitled as metabolic-dysfunction associated fatty liver disease (MAFLD). Therefore anthropometric indicators of adiposity may provide a non-invasive predictive and diagnostic tool for...
6.
Tan Q, Qin C, Yang J, Wang T, Lin H, Lin C, et al.
BMC Neurol . 2021 Jul; 21(1):292. PMID: 34311729
Purpose: To obtain normal ranges for the inner diameters of the carotid arteries. Methods: This retrospective analysis included consecutive patients with disease-free carotid arteries who had undergone 3D-DSA at two...
7.
Zhao Z, Jiang Y, Li L, Chen Y, Li Y, Lan Q, et al.
ACS Omega . 2021 Jan; 5(51):33421-33432. PMID: 33403304
: Human urate transporter 1 (hURAT1) is the most pivotal therapeutic target for treating hyperuricemia. However, the molecular interactions between uric acid and URAT1 are still unknown due to lack...
8.
Chen Y, Zhao Z, Li Y, Yang Y, Li L, Jiang Y, et al.
Phytomedicine . 2020 Oct; 80:153374. PMID: 33075645
Background: Insufficient renal urate excretion and/or overproduction of uric acid (UA) are the dominant causes of hyperuricemia. Baicalein (BAL) is widely distributed in dietary plants and has extensive biological activities,...
9.
Ye Z, Liu Y, Deng X, Chen X, Lin C, Tang Y, et al.
Med Sci Monit . 2016 Aug; 22:2924-33. PMID: 27542158
BACKGROUND This retrospective clinical investigation aimed to evaluate the short-term effectiveness and safety of SBCAS for symptomatic bilateral high-grade CS. MATERIAL AND METHODS From 2009 to 2014, 145 patients were...
10.
Tang Y, Ye Z, Wei Y, Lin C, Wang Y, Qin C
J Mol Neurosci . 2014 Jun; 55(2):324-34. PMID: 24894590
Collapsin response mediator proteins (CRMPs) family predominantly expressed in the developing nervous system as key molecular components in shaping neural networks. However, knowledge of the evolution of CRMPs is limited....