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Crystal N Wilson

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Recent Articles
1.
McClellan B, Wilson C, Brenner A, Jolly C, deGraffenried L
Oncogene . 2024 Feb; 43(14):1063-1074. PMID: 38374406
Flotillin-1 contributes to invasion and metastasis in triple negative breast cancer (TNBC) and is modified post-translationally through palmitoylation. Palmitoylation, the process of conjugating palmitoyl-CoA to proteins, plays an essential role...
2.
Lu M, Busquets J, Impedovo V, Wilson C, Chan H, Chang Y, et al.
Cell Metab . 2024 Feb; 36(4):808-821.e6. PMID: 38354740
SLC25A51 selectively imports oxidized NAD into the mitochondrial matrix and is required for sustaining cell respiration. We observed elevated expression of SLC25A51 that correlated with poorer outcomes in patients with...
3.
Goyal S, Paspureddi A, Lu M, Chan H, Lyons S, Wilson C, et al.
EMBO Rep . 2023 Aug; 24(10):e56596. PMID: 37575034
SLC25A51 is a member of the mitochondrial carrier family (MCF) but lacks key residues that contribute to the mechanism of other nucleotide MCF transporters. Thus, how SLC25A51 transports NAD across...
4.
Li H, Liu Y, Xiao Y, Wilson C, Bai H, Jones M, et al.
Proc Natl Acad Sci U S A . 2023 Feb; 120(6):e2212072120. PMID: 36724254
Cancer treatments targeting DNA repair deficiencies often encounter drug resistance, possibly due to alternative metabolic pathways that counteract the most damaging effects. To identify such alternative pathways, we screened for...
5.
Liu Y, Li H, Wilson C, Bai H, Boufraqech M, Weyemi U
Sci Rep . 2022 Mar; 12(1):3758. PMID: 35260660
Genomic stability is essential for organismal development, cellular homeostasis, and survival. The DNA double-strand breaks are particularly deleterious, creating an environment prone to cellular transformation and oncogenic activation. The histone...