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Cristina Patassini

Explore the profile of Cristina Patassini including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 367
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Recent Articles
1.
Girardi L, Patassini C, Miravet Valenciano J, Sato Y, Fagundes Cagnin N, Castellon J, et al.
J Assist Reprod Genet . 2024 Oct; 41(12):3357-3370. PMID: 39378000
Purpose: We aimed to identify the correlation between morphological pronuclear (PN) status and the genetically determined ploidy configuration in preimplantation embryos. Methods: A retrospective observational study was conducted on 1982...
2.
Girardi L, Figliuzzi M, Poli M, Serdarogullari M, Patassini C, Caroselli S, et al.
Hum Reprod . 2023 Mar; 38(5):982-991. PMID: 36928183
Study Question: How well can whole chromosome copy number analysis from a single trophectoderm (TE) biopsy predict true mosaicism configurations in human blastocysts? Summary Answer: When a single TE biopsy...
3.
Capalbo A, Buonaiuto S, Figliuzzi M, Damaggio G, Girardi L, Caroselli S, et al.
Reprod Biomed Online . 2022 Jul; 45(3):508-518. PMID: 35798635
Research Question: Can a methodology be developed for case selection and whole-exome sequencing (WES) analysis of women who are infertile owing to recurrent oocyte maturation defects (OOMD) and/or preimplantation embryo...
4.
Picchetta L, Caroselli S, Figliuzzi M, Cogo F, Zambon P, Costa M, et al.
J Assist Reprod Genet . 2022 Feb; 39(4):847-860. PMID: 35124783
The most important factor associated with oocytes' developmental competence has been widely identified as the presence of chromosomal abnormalities. However, growing application of genome-wide sequencing (GS) in population diagnostics has...
5.
Capalbo A, Poli M, Rienzi L, Girardi L, Patassini C, Fabiani M, et al.
Am J Hum Genet . 2021 Nov; 108(12):2238-2247. PMID: 34798051
Chromosome imbalance (aneuploidy) is the major cause of pregnancy loss and congenital disorders in humans. Analyses of small biopsies from human embryos suggest that aneuploidy commonly originates during early divisions,...
6.
Girardi L, Serdarogullari M, Patassini C, Poli M, Fabiani M, Caroselli S, et al.
Am J Hum Genet . 2020 Mar; 106(4):525-534. PMID: 32220293
Despite next-generation sequencing, which now allows for the accurate detection of segmental aneuploidies from in vitro fertilization embryo biopsies, the origin and characteristics of these aneuploidies are still relatively unknown....
7.
Poli M, Girardi L, Fabiani M, Moretto M, Romanelli V, Patassini C, et al.
Front Endocrinol (Lausanne) . 2019 Apr; 10:154. PMID: 30941103
Recent advancements in genomic analysis allow testing of an increasing number of genetic features in human preimplantation embryos. Typical single gene mutation and whole chromosomes testing can now be integrated...
8.
Capalbo A, Romanelli V, Patassini C, Poli M, Girardi L, Giancani A, et al.
Fertil Steril . 2018 Oct; 110(5):870-879.e5. PMID: 30316433
Objective: To determine whether blastocoel fluid (BF) or spent blastocyst medium (SBM) is a suitable template for genotype and/or karyotype assessment of in vitro fertilization-generated embryos. Design: Prospective blinded study....
9.
Cimadomo D, Rienzi L, Romanelli V, Alviggi E, Levi-Setti P, Albani E, et al.
Hum Reprod . 2018 Sep; 33(10):1839-1846. PMID: 30239718
Study Question: Can a second round of biopsy, vitrification and chromosomal testing provide a valid diagnosis where the first attempt fails? Summary Answer: The risk of inconclusive chromosomal-assessment after trophectoderm...
10.
Capalbo A, Ubaldi F, Cimadomo D, Maggiulli R, Patassini C, Dusi L, et al.
Hum Reprod . 2015 Dec; 31(1):199-208. PMID: 26637492
Study Question: Is blastocyst biopsy and quantitative real-time PCR based comprehensive chromosome screening a consistent and reproducible approach across different biopsy practitioners? Summary Answer: The blastocyst biopsy approach provides highly...