Cristina Cigana
Overview
Explore the profile of Cristina Cigana including associated specialties, affiliations and a list of published articles.
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Articles
40
Citations
924
Followers
0
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Recent Articles
1.
Pagani I, Venturini A, Capurro V, Nonis A, Ghezzi S, Lena M, et al.
Am J Respir Cell Mol Biol
. 2024 Sep;
72(3):308-319.
PMID: 39311876
The coronavirus disease (COVID-19) pandemic has underscored the impact of viral infections on individuals with cystic fibrosis (CF). Initial observations suggested lower COVID-19 rates among CF populations; however, subsequent clinical...
2.
Cigana C, Rossi A, Alcala-Franco B, Bragonzi A
Methods Mol Biol
. 2023 Oct;
2721:215-231.
PMID: 37819525
Disease-specific animal models and treatment regimens are essential to optimize anti-Pseudomonas drug testing. Mouse models of acute and chronic P. aeruginosa infections provide valuable resources that mimic the initial and...
3.
Cigana C, Giannella R, Colavolpe A, Alcala-Franco B, Mancini G, Colombi F, et al.
Microbiol Spectr
. 2023 Jan;
11(1):e0408322.
PMID: 36625583
Cystic fibrosis transmembrane conductance regulator (CFTR) modulators improve clinical outcomes with varied efficacies in patients with CF. However, the mutual effects of CFTR modulators and bacterial adaptation, together with antibiotic...
4.
De Leo F, Rossi A, De Marchis F, Cigana C, Melessike M, Quilici G, et al.
Mol Med
. 2022 Sep;
28(1):108.
PMID: 36071400
Background: High-mobility group box 1 protein (HMGB1) is an ubiquitous nuclear protein that once released in the extracellular space acts as a Damage Associated Molecular Pattern and promotes inflammation. HMGB1...
5.
Rigauts C, Aizawa J, Taylor S, Rogers G, Govaerts M, Cos P, et al.
Eur Respir J
. 2021 Sep;
59(5).
PMID: 34588194
Background: Chronic airway inflammation is the main driver of pathogenesis in respiratory diseases such as severe asthma, chronic obstructive pulmonary disease, cystic fibrosis (CF) and bronchiectasis. While the role of...
6.
Fenn S, Dubern J, Cigana C, De Simone M, Lazenby J, Juhas M, et al.
mBio
. 2021 Apr;
12(2).
PMID: 33879591
The opportunistic pathogen produces an arsenal of virulence factors causing a wide range of diseases in multiple hosts and is difficult to eradicate due to its intrinsic resistance to antibiotics....
7.
Saliu F, Rizzo G, Bragonzi A, Cariani L, Cirillo D, Colombo C, et al.
ERJ Open Res
. 2021 Mar;
7(1).
PMID: 33778054
Nontypeable (NTHi) is commonly isolated from airways of patients suffering from chronic respiratory diseases, such as COPD or cystic fibrosis (CF). However, to what extent NTHi long-term infection contributes to...
8.
Cigana C, Castandet J, Sprynski N, Melessike M, Beyria L, Ranucci S, et al.
Front Microbiol
. 2021 Jan;
11:620819.
PMID: 33510733
Chronic infection by in cystic fibrosis (CF) patients is a major contributor to progressive lung damage and is poorly treated by available antibiotic therapy. An alternative approach to the development...
9.
Ferrara S, Rossi A, Ranucci S, De Fino I, Bragonzi A, Cigana C, et al.
mSphere
. 2020 Oct;
5(5).
PMID: 33055260
Bacterial small RNAs play a remarkable role in the regulation of functions involved in host-pathogen interaction. ErsA is a small RNA of that contributes to the regulation of bacterial virulence...
10.
Riva C, Tortoli E, Cugnata F, Sanvito F, Esposito A, Rossi M, et al.
Int J Mol Sci
. 2020 Sep;
21(18).
PMID: 32916885
Pulmonary infections caused by (MA) have increased over recent decades, affecting individuals with underlying pathologies such as chronic obstructive pulmonary disease, bronchiectasis and, especially, cystic fibrosis. The lack of a...