Craig S Rosenfeld
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Explore the profile of Craig S Rosenfeld including associated specialties, affiliations and a list of published articles.
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4
Citations
3732
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Recent Articles
1.
Brown J, Xu H, Duggan E, Rosenfeld C, Van Remmen H
J Physiol
. 2025 Jan;
603(4):837-854.
PMID: 39777675
We previously reported that elevated expression of phospholipid hydroperoxide glutathione peroxidase 4, an enzyme that regulates membrane lipid hydroperoxides, can mitigate sarcopenia in mice. However, it is still unknown whether...
2.
Stockwell B, Friedmann Angeli J, Bayir H, Bush A, Conrad M, Dixon S, et al.
Cell
. 2017 Oct;
171(2):273-285.
PMID: 28985560
Ferroptosis is a form of regulated cell death characterized by the iron-dependent accumulation of lipid hydroperoxides to lethal levels. Emerging evidence suggests that ferroptosis represents an ancient vulnerability caused by...
3.
Kantarjian H, Issa J, Rosenfeld C, Bennett J, Albitar M, DiPersio J, et al.
Cancer
. 2006 Mar;
106(8):1794-803.
PMID: 16532500
Background: Aberrant DNA methylation, which results in leukemogenesis, is frequent in patients with myelodysplastic syndromes (MDS) and is a potential target for pharmacologic therapy. Decitabine indirectly depletes methylcytosine and causes...
4.
Rosenfeld C
Semin Oncol
. 2005 Oct;
32(5):465-72.
PMID: 16210087
This review highlights decitabine as a prototype epigenetic modifying drug to show how the clinical development of epigenetic agents differs from that of traditional cytotoxic chemotherapies. Decitabine, a cytosine analogue,...
5.
Issa J, Garcia-Manero G, Giles F, Mannari R, Thomas D, Faderl S, et al.
Blood
. 2003 Nov;
103(5):1635-40.
PMID: 14604977
Decitabine (5-aza-2'-deoxycytidine) inhibits DNA methylation and has dual effects on neoplastic cells, including the reactivation of silenced genes and differentiation at low doses and cytotoxicity at high doses. We evaluated,...