Craig S Nowell
Overview
Explore the profile of Craig S Nowell including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
653
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Recent Articles
1.
Nowell C, Radtke F
J Cell Sci
. 2017 Feb;
130(6):1021-1025.
PMID: 28202689
The corneal epithelium acts as a protective barrier on the anterior ocular surface and is essential for maintaining transparency of the cornea and thus visual acuity. During both homeostasis and...
2.
Nowell C, Radtke F
Nat Rev Cancer
. 2017 Feb;
17(3):145-159.
PMID: 28154375
The Notch signalling cascade is an evolutionarily conserved pathway that has a crucial role in regulating development and homeostasis in various tissues. The cellular processes and events that it controls...
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4.
ONeill K, Bredenkamp N, Tischner C, Vaidya H, Stenhouse F, Peddie C, et al.
PLoS One
. 2016 Mar;
11(3):e0151666.
PMID: 26983083
Thymus function requires extensive cross-talk between developing T-cells and the thymic epithelium, which consists of cortical and medullary TEC. The transcription factor FOXN1 is the master regulator of TEC differentiation...
5.
Nowell C, Odermatt P, Azzolin L, Hohnel S, Wagner E, Fantner G, et al.
Nat Cell Biol
. 2015 Dec;
18(2):168-80.
PMID: 26689676
Chronic inflammation is associated with a variety of pathological conditions in epithelial tissues, including cancer, metaplasia and aberrant wound healing. In relation to this, a significant body of evidence suggests...
6.
Jin X, Nowell C, Ulyanchenko S, Stenhouse F, Blackburn C
PLoS One
. 2014 Dec;
9(12):e114842.
PMID: 25531271
Normal thymus function reflects interactions between developing T-cells and several thymic stroma cell types. Within the stroma, key functions reside in the distinct cortical and medullary thymic epithelial cell (TEC)...
7.
Bredenkamp N, Nowell C, Blackburn C
Development
. 2014 Apr;
141(8):1627-37.
PMID: 24715454
Thymic involution is central to the decline in immune system function that occurs with age. By regenerating the thymus, it may therefore be possible to improve the ability of the...
8.
Sarode B, Nowell C, Ihm J, Kostic C, Arsenijevic Y, Moulin A, et al.
Pigment Cell Melanoma Res
. 2014 Mar;
27(4):580-9.
PMID: 24628886
The ciliary body and iris are pigmented epithelial structures in the anterior eye segment that function to maintain correct intra-ocular pressure and regulate exposure of the internal eye structures to...
9.
Di Piazza M, Nowell C, Koch U, Durham A, Radtke F
Cancer Cell
. 2012 Oct;
22(4):479-93.
PMID: 23079658
Inflammation can promote or inhibit cancer progression. In this study we have addressed the role of the proinflammatory cytokine thymic stromal lymphopoietin (TSLP) during skin carcinogenesis. Using conditional loss- and...
10.
Nowell C, Bredenkamp N, Tetelin S, Jin X, Tischner C, Vaidya H, et al.
PLoS Genet
. 2011 Nov;
7(11):e1002348.
PMID: 22072979
The forkhead transcription factor Foxn1 is indispensable for thymus development, but the mechanisms by which it mediates thymic epithelial cell (TEC) development are poorly understood. To examine the cellular and...