Craig P Giacomini
Overview
Explore the profile of Craig P Giacomini including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
697
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0
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Recent Articles
1.
Azimi M, Yee S, Riselli A, Silva D, Giacomini C, Giacomini K, et al.
J Vet Pharmacol Ther
. 2023 May;
46(6):401-412.
PMID: 37198956
The ATP-binding cassette transporter P-glycoprotein (P-gp) limits the oral bioavailability of many drugs. Although P-gp has been well studied in humans and mice, little is known about the substrate specificities...
2.
Shain A, Salari K, Giacomini C, Pollack J
BMC Genomics
. 2013 Sep;
14:624.
PMID: 24041470
Background: Pancreatic cancer is a deadly disease with a five-year survival of less than 5%. A better understanding of the underlying biology may suggest novel therapeutic targets. Recent surveys of...
3.
Giacomini C, Jeffrey R, Shin L
Semin Ultrasound CT MR
. 2013 Jun;
34(3):236-47.
PMID: 23768890
Head and neck malignancies, including squamous cell carcinoma, lymphoma, and thyroid cancer, are a major cause of morbidity and mortality worldwide and frequently present with cervical lymphadenopathy. Distinguishing normal from...
4.
Giacomini C, Sun S, Varma S, Shain A, Giacomini M, Balagtas J, et al.
PLoS Genet
. 2013 May;
9(4):e1003464.
PMID: 23637631
Gene fusions, like BCR/ABL1 in chronic myelogenous leukemia, have long been recognized in hematologic and mesenchymal malignancies. The recent finding of gene fusions in prostate and lung cancers has motivated...
5.
Salari K, Spulak M, Cuff J, Forster A, Giacomini C, Huang S, et al.
Proc Natl Acad Sci U S A
. 2012 Nov;
109(46):E3196-205.
PMID: 23112155
The mutational activation of oncogenes drives cancer development and progression. Classic oncogenes, such as MYC and RAS, are active across many different cancer types. In contrast, "lineage-survival" oncogenes represent a...
6.
Brunner A, Beck A, Edris B, Sweeney R, Zhu S, Li R, et al.
Genome Biol
. 2012 Aug;
13(8):R75.
PMID: 22929540
Background: Molecular characterization of tumors has been critical for identifying important genes in cancer biology and for improving tumor classification and diagnosis. Long non-coding RNAs, as a new, relatively unstudied...
7.
Del Vecchio C, Jensen K, Nitta R, Shain A, Giacomini C, Wong A
Cancer Res
. 2012 Mar;
72(10):2657-71.
PMID: 22419663
EGFRvIII is a tumor-specific variant of the epidermal growth factor receptor (EGFR). Although EGFRvIII is most commonly found in glioblastoma, its expression in other tumor types remains controversial. In this...
8.
Shain A, Giacomini C, Matsukuma K, Karikari C, Bashyam M, Hidalgo M, et al.
Proc Natl Acad Sci U S A
. 2012 Jan;
109(5):E252-9.
PMID: 22233809
Defining the molecular genetic alterations underlying pancreatic cancer may provide unique therapeutic insight for this deadly disease. Toward this goal, we report here an integrative DNA microarray and sequencing-based analysis...
9.
Kwei K, Bashyam M, Kao J, Ratheesh R, Reddy E, Kim Y, et al.
PLoS Genet
. 2008 Jun;
4(5):e1000081.
PMID: 18535672
Pancreatobiliary cancers have among the highest mortality rates of any cancer type. Discovering the full spectrum of molecular genetic alterations may suggest new avenues for therapy. To catalogue genomic alterations,...
10.
Lapointe J, Malhotra S, Higgins J, Bair E, Thompson M, Salari K, et al.
Am J Surg Pathol
. 2008 Jan;
32(2):205-9.
PMID: 18223322
Growing evidence suggests that only a fraction of prostate cancers detected clinically are potentially lethal. An important clinical issue is identifying men with indolent cancer who might be spared aggressive...