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Craig N Morrell

Explore the profile of Craig N Morrell including associated specialties, affiliations and a list of published articles. Areas
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Articles 94
Citations 2581
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Recent Articles
11.
Wang S, Singh M, Yang H, Morrell C, Mohamad L, Xu J, et al.
bioRxiv . 2023 May; PMID: 37131726
Background: In people living with HIV (PLWH) on combination antiretroviral therapy (cART), persistent systemic inflammation is a driving force for the progression of comorbidities, such as cardiovascular and cerebrovascular diseases....
12.
Livada A, Pariser D, Morrell C
Res Pract Thromb Haemost . 2023 Apr; 7(2):100053. PMID: 37063766
A state of the art lecture titled "" was presented at the London International Society on Thrombosis and Haemostasis congress in 2022. This lecture highlighted that although most medical teaching...
13.
Maurya P, Ture S, Li C, Scheible K, McGrath K, Palis J, et al.
Arterioscler Thromb Vasc Biol . 2023 Mar; 43(6):873-885. PMID: 36951062
Background: Thrombocytopenia is common in preterm neonates. Platelet transfusions are sometimes given to thrombocytopenic neonates with the hope of reducing the bleeding risk, however, there are little clinical data to...
14.
Castell N, Guerrero-Martin S, Rubin L, Shirk E, Brockhurst J, Lyons C, et al.
Psychosom Med . 2022 Sep; 84(8):966-975. PMID: 36162063
Objective: Simian immunodeficiency virus (SIV) infection of macaques recapitulates many aspects of HIV pathogenesis and is similarly affected by both genetic and environmental factors. Psychosocial stress is associated with immune...
15.
Morrell C, Mix D, Aggarwal A, Bhandari R, Godwin M, Owens 3rd P, et al.
J Clin Invest . 2022 Mar; 132(9). PMID: 35324479
As blood transitions from steady laminar flow (S-flow) in healthy arteries to disturbed flow (D-flow) in aneurysmal arteries, platelets are subjected to external forces. Biomechanical platelet activation is incompletely understood...
16.
Koupenova M, Livada A, Morrell C
Circ Res . 2022 Jan; 130(2):288-308. PMID: 35050690
Classically, platelets have been described as the cellular blood component that mediates hemostasis and thrombosis. This important platelet function has received significant research attention for >150 years. The immune cell...
17.
Vega Ocasio D, Stewart-Ibarra A, Sippy R, Li C, McCue K, Bendinskas K, et al.
Am J Trop Med Hyg . 2021 Aug; 105(3):756-765. PMID: 34339390
Aedes aegypti, the mosquito that transmits arboviral diseases such as dengue (DENV), chikungunya (CHIKV), and Zika viruses (ZIKV), is present in tropical and subtropical regions of the world. Individuals at...
18.
Guo L, Shen S, Rowley J, Tolley N, Jia W, Manne B, et al.
Blood . 2021 Apr; 138(5):401-416. PMID: 33895821
Circulating platelets interact with leukocytes to modulate host immune and thrombotic responses. In sepsis, platelet-leukocyte interactions are increased and have been associated with adverse clinical events, including increased platelet-T-cell interactions....
19.
Kim C, Yea K, Morrell C, Jeong Y, Lowenstein C
Biochem Biophys Res Commun . 2021 Apr; 558:29-35. PMID: 33895548
Estrogen therapy is used to treat patients with post-menopausal symptoms, such as hot flashes and dyspareunia. Estrogen therapy also decreases the risk of fractures from osteoporosis in post-menopausal women. However,...
20.
Hilt Z, Maurya P, Tesoro L, Pariser D, Ture S, Cleary S, et al.
Circ Res . 2021 Jan; 128(5):655-669. PMID: 33508948
Rationale: Circulating monocytes can have proinflammatory or proreparative phenotypes. The endogenous signaling molecules and pathways that regulate monocyte polarization in vivo are poorly understood. We have shown that platelet-derived β2M...