Cosmas C Giallourakis
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Explore the profile of Cosmas C Giallourakis including associated specialties, affiliations and a list of published articles.
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14
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2431
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Recent Articles
1.
Zhou C, Molinie B, Daneshvar K, Pondick J, Wang J, Van Wittenberghe N, et al.
Cell Rep
. 2017 Aug;
20(9):2262-2276.
PMID: 28854373
N-methyladenosine (mA) is the most abundant internal modification of mRNAs and is implicated in all aspects of post-transcriptional RNA metabolism. However, little is known about mA modifications to circular (circ)...
2.
Molinie B, Giallourakis C
Methods Mol Biol
. 2017 Mar;
1562:45-53.
PMID: 28349453
N-methyladenosine-sequencing (mA-seq) is a critical tool to obtain an unbiased genome-wide picture of mA sites of modification at high resolution. It allows the study of the impact of various perturbations...
3.
Molinie B, Wang J, Lim K, Hillebrand R, Lu Z, Van Wittenberghe N, et al.
Nat Methods
. 2016 Jul;
13(8):692-8.
PMID: 27376769
N(6)-Methyladenosine (m(6)A) is a widespread, reversible chemical modification of RNA molecules, implicated in many aspects of RNA metabolism. Little quantitative information exists as to either how many transcript copies of...
4.
Sigova A, Abraham B, Ji X, Molinie B, Hannett N, Guo Y, et al.
Science
. 2015 Oct;
350(6263):978-81.
PMID: 26516199
Transcription factors (TFs) bind specific sequences in promoter-proximal and -distal DNA elements to regulate gene transcription. RNA is transcribed from both of these DNA elements, and some DNA binding TFs...
5.
Batista P, Molinie B, Wang J, Qu K, Zhang J, Li L, et al.
Cell Stem Cell
. 2014 Dec;
15(6):707-19.
PMID: 25456834
N6-methyl-adenosine (m(6)A) is the most abundant modification on messenger RNAs and is linked to human diseases, but its functions in mammalian development are poorly understood. Here we reveal the evolutionary...
6.
Giallourakis C
Gastroenterol Hepatol (N Y)
. 2014 Apr;
9(4):244-6.
PMID: 24711770
No abstract available.
7.
Macdonald L, Karow M, Stevens S, Auerbach W, Poueymirou W, Yasenchak J, et al.
Proc Natl Acad Sci U S A
. 2014 Apr;
111(14):5147-52.
PMID: 24706858
Genetic humanization, which involves replacing mouse genes with their human counterparts, can create powerful animal models for the study of human genes and diseases. One important example of genetic humanization...
8.
Marouf F, Giallourakis C, Baer L, Hanau M, Holbert B
N Engl J Med
. 2013 Oct;
369(17):1639-47.
PMID: 24152264
No abstract available.
9.
Giallourakis C, Benita Y, Molinie B, Cao Z, Despo O, Pratt H, et al.
J Immunol
. 2013 Apr;
190(11):5578-87.
PMID: 23616578
Profiling studies of mRNA and microRNA, particularly microarray-based studies, have been extensively used to create compendia of genes that are preferentially expressed in the immune system. In some instances, functional...
10.
Sigova A, Mullen A, Molinie B, Gupta S, Orlando D, Guenther M, et al.
Proc Natl Acad Sci U S A
. 2013 Feb;
110(8):2876-81.
PMID: 23382218
Many long noncoding RNA (lncRNA) species have been identified in mammalian cells, but the genomic origin and regulation of these molecules in individual cell types is poorly understood. We have...