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Cositha Santhakumar

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Articles 10
Citations 103
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Recent Articles
1.
Marsh-Wakefield F, Santhakumar C, Ferguson A, Ashhurst T, Shin J, Guan F, et al.
Hepatol Commun . 2025 Jan; 8(11. PMID: 39761010
Background: HCC develops in the context of chronic inflammation; however, the opposing roles the immune system plays in both the development and control of tumors are not fully understood. Mapping...
2.
Liu K, Dennis C, Prince D, Marsh-Wakefield F, Santhakumar C, Gamble J, et al.
JHEP Rep . 2023 Jul; 5(8):100792. PMID: 37456680
Vessels that encapsulate tumour clusters (VETC) is a distinct histologic vascular pattern associated with a novel mechanism of metastasis. First described in human cancers in 2004, its prevalence and prognostic...
3.
Marsh-Wakefield F, Ferguson A, Liu K, Santhakumar C, McCaughan G, Palendira U
Ther Adv Med Oncol . 2022 Jul; 14:17588359221113270. PMID: 35898965
Hepatocellular carcinoma (HCC) is a common and deadly cancer worldwide. Many factors contribute to mortality and place an individual at high risk of developing HCC, including viral infection, alcohol intake,...
4.
Santhakumar C, Ormiston W, McCall J, Bartlett A, Duncan D, Holden A
CVIR Endovasc . 2022 Jul; 5(1):36. PMID: 35869399
Background: Preoperative portal vein embolization (PVE) is widely used prior to major liver resection to reduce the risk of post-hepatectomy liver failure (PHLF). We evaluated the efficacy and safety of...
5.
Kortt N, Santhakumar C, Davis R, Strasser S, McCaughan G, Liu K, et al.
Transpl Infect Dis . 2021 Nov; 24(1):e13758. PMID: 34762768
Background And Aim: Data are limited on whether Clostridioides difficile infection (CDI) in the first year after liver transplantation (LT) is associated with increased mortality. In an Australian setting without...
6.
Santhakumar C, Gane E, Liu K, McCaughan G
Hepatol Int . 2020 Nov; 14(6):947-957. PMID: 33188512
Hepatocellular carcinoma (HCC) is a heterogeneous inflammation-driven malignancy, which, despite significant advances in management, continues to portend a poor prognosis. Recent advances in basic and translational research have increasingly defined...
7.
Chan M, McDonald S, Ong Y, Mastrocostas K, Ho E, Huo Y, et al.
Eur Radiol Exp . 2019 Dec; 3(1):49. PMID: 31853685
Background: Hepatocellular carcinoma (HCC) guidelines recommend ultrasound screening in high-risk patients. However, in some patients, ultrasound image quality is suboptimal due to factors such as hepatic steatosis, cirrhosis, and confounding...
8.
van der Poorten D, McLeod D, Ahlenstiel G, Read S, Kwok A, Santhakumar C, et al.
J Clin Immunol . 2018 Sep; 38(7):768-777. PMID: 30219982
Individuals with common variable immunodeficiency (CVID) have an increased risk of gastric cancer, and gastrointestinal lymphoma, yet screening for premalignant gastric lesions is rarely offered routinely to these patients. Proposed...
9.
Santhakumar C, Faddoul C, Barker R, Facer R, Limaye S
Clin Med (Lond) . 2016 Apr; 16(2):199-200. PMID: 27037395
A 58-year-old man was referred for review due to the finding of splinter haemorrhages and digital infarcts. Further questioning revealed a history of unintentional weight loss and calf pain. There...
10.
Santhakumar C, Liu K
World J Gastrointest Pathophysiol . 2014 Nov; 5(4):479-86. PMID: 25400992
Obscure gastrointestinal bleeding (OGIB) is defined as recurrent or persistent bleeding or presence of iron deficiency anaemia after evaluation with a negative bidirectional endoscopy. OGIB accounts for 5% of gastrointestinal...