Corey D Clay
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Explore the profile of Corey D Clay including associated specialties, affiliations and a list of published articles.
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12
Citations
410
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Recent Articles
1.
Clay C, Strait R, Mahler A, Khodoun M, Finkelman F
J Allergy Clin Immunol
. 2017 Jun;
141(4):1373-1381.e5.
PMID: 28624610
Background: The inhibitory receptor FcγRIIB is expressed on human and murine bone marrow-derived cells and limits inflammation by suppressing signaling through stimulatory receptors. Objective: We sought to evaluate the effects...
2.
Rapid desensitization of mice with anti-FcγRIIb/FcγRIII mAb safely prevents IgG-mediated anaphylaxis
Khodoun M, Kucuk Z, Strait R, Krishnamurthy D, Janek K, Clay C, et al.
J Allergy Clin Immunol
. 2013 Oct;
132(6):1375-87.
PMID: 24139828
Background: Stimulatory IgG receptors (FcγRs) on bone marrow-derived cells contribute to the pathogenesis of several autoimmune and inflammatory disorders. Monoclonal antibodies that block FcγRs might suppress these diseases, but they...
3.
Mohapatra N, Soni S, Rajaram M, Dang P, Reilly T, El-Benna J, et al.
J Immunol
. 2010 Mar;
184(9):5141-50.
PMID: 20348422
Francisella tularensis contains four putative acid phosphatases that are conserved in Francisella novicida. An F. novicida quadruple mutant (AcpA, AcpB, AcpC, and Hap [DeltaABCH]) is unable to escape the phagosome...
4.
Cremer T, Ravneberg D, Clay C, Piper-Hunter M, Marsh C, Elton T, et al.
PLoS One
. 2009 Dec;
4(12):e8508.
PMID: 20041145
The intracellular gram-negative bacterium Francisella tularensis causes the disease tularemia and is known for its ability to subvert host immune responses. Previous work from our laboratory identified the PI3K/Akt pathway...
5.
Premanandan C, Storozuk C, Clay C, Lairmore M, Schlesinger L, Phipps A
Microb Pathog
. 2009 Mar;
46(6):306-14.
PMID: 19328844
Alveolar macrophages are thought to play a central role in the pathogenesis of inhalational anthrax. Receptors present on macrophages that mediate phagocytosis of Bacillus anthracis spores have yet to be...
6.
Clay C, Soni S, Gunn J, Schlesinger L
J Immunol
. 2008 Oct;
181(8):5568-78.
PMID: 18832715
The bacterium Francisella tularensis (Ft) is a potential weapon of bioterrorism when aerosolized. Macrophage infection is necessary for disease progression and efficient phagocytosis by human macrophages requires serum opsonization by...
7.
Butchar J, Cremer T, Clay C, Gavrilin M, Wewers M, Marsh C, et al.
PLoS One
. 2008 Aug;
3(8):e2924.
PMID: 18698339
Francisella tularensis is a gram-negative facultative bacterium that causes the disease tularemia, even upon exposure to low numbers of bacteria. One critical characteristic of Francisella is its ability to dampen...
8.
Butchar J, Rajaram M, Ganesan L, Parsa K, Clay C, Schlesinger L, et al.
J Immunol
. 2007 Mar;
178(7):4445-54.
PMID: 17372002
Francisella tularensis, the causative agent of tularemia, is phagocytosed by immune cells such as monocytes and macrophages. Instead of being destroyed in the phagolysosome, the bacterium escapes the phagosome and...
9.
Genter M, Clay C, Dalton T, Dong H, Nebert D, Shertzer H
Biochem Biophys Res Commun
. 2006 Mar;
342(4):1375-81.
PMID: 16516144
TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) induces cytochromes P450 (CYPs) such as CYP1A1 and CYP1A2 via activation of the aromatic hydrocarbon receptor (AHR). Herein we describe the TCDD-dependent enrichment of CYPs in liver microsomes...
10.
Shertzer H, Clay C, Genter M, Chames M, Schneider S, Oakley G, et al.
Free Radic Biol Med
. 2004 Feb;
36(5):618-31.
PMID: 14980705
Studying liver microsomes from 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced or vehicle-treated (noninduced) mice, we evaluated the in vitro effects of added chemicals on the production of reactive oxygen due to substrate/P450-mediated uncoupling. The...