Corey A Scipione
Overview
Explore the profile of Corey A Scipione including associated specialties, affiliations and a list of published articles.
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20
Citations
515
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Recent Articles
1.
Patel S, Ellis K, Scipione C, Fish J, Howe K
Front Cardiovasc Med
. 2025 Feb;
11:1506360.
PMID: 39906338
Aging significantly affects intercellular communication between vascular endothelial cells (ECs) and hematopoietic cells, leading to vascular inflammation and age-associated diseases. This study determined how senescent ECs communicate with monocytes, whether...
2.
Polenz C, Scipione C, Hyduk S, Althagafi M, Ibrahim H, Cybulsky M
Arterioscler Thromb Vasc Biol
. 2024 Feb;
44(4):883-897.
PMID: 38328936
Background: Myeloid cells (MCs) reside in the aortic intima at regions predisposed to atherosclerosis. Systemic inflammation triggers reverse transendothelial migration (RTM) of intimal MCs into the arterial blood, which orchestrates...
3.
Ting K, Yu P, Dow R, Floro E, Ibrahim H, Scipione C, et al.
J Immunol
. 2023 Sep;
211(10):1561-1577.
PMID: 37756544
Lipid accumulation in macrophages (Mφs) is a hallmark of atherosclerosis, yet how lipid accumulation affects inflammatory responses through rewiring of Mφ metabolism is poorly understood. We modeled lipid accumulation in...
4.
Scipione C, Hyduk S, Polenz C, Cybulsky M
Can J Cardiol
. 2023 Sep;
39(12):1781-1794.
PMID: 37716639
High-resolution single-cell technologies have shed light on the pathogenesis of cardiovascular diseases by enabling the discovery of novel cellular and transcriptomic signatures associated with various conditions, and uncovering new contributions...
5.
Roubtsova A, Scipione C, Garcon D, Boffa M, Seidah N, Koschinsky M, et al.
Biochim Biophys Acta Mol Cell Biol Lipids
. 2023 Jan;
1868(4):159288.
PMID: 36708961
No abstract available.
6.
Scipione C, Cybulsky M
Curr Opin Lipidol
. 2022 Aug;
33(5):271-276.
PMID: 35979994
Purpose Of Review: To highlight recent conceptual and technological advances that have positioned the field to interrogate the cellular and molecular mechanisms contributing to the initiation of atherosclerosis, including intimal...
7.
Bourgeois R, Bourgault J, Despres A, Perrot N, Guertin J, Girard A, et al.
Metabolites
. 2021 Aug;
11(7).
PMID: 34357353
Lipoprotein(a) (Lp(a)) is one of the most important risk factors for the development of calcific aortic valve stenosis (CAVS). However, the mechanisms through which Lp(a) causes CAVS are currently unknown....
8.
Bourgeois R, Girard A, Perrot N, Guertin J, Mitchell P, Couture C, et al.
CJC Open
. 2021 May;
3(4):450-459.
PMID: 34027348
Background: Lipoprotein(a) (Lp[a]), which consists of a low-density lipoprotein (LDL) bound to apolipoprotein(a), is one of the strongest genetic risk factors for atherosclerotic cardiovascular diseases. Few studies have performed hypothesis-free...
9.
Jongstra-Bilen J, Tai K, Althagafi M, Siu A, Scipione C, Karim S, et al.
J Mol Cell Cardiol
. 2021 Mar;
156:69-78.
PMID: 33781821
One of the hallmarks of atherosclerosis is ongoing accumulation of macrophages in the artery intima beginning at disease onset. Monocyte recruitment contributes to increasing macrophage abundance at early stages of...
10.
Ikeda J, Scipione C, Hyduk S, Althagafi M, Atif J, Dick S, et al.
Circ Res
. 2021 Jan;
128(4):530-543.
PMID: 33397122
Rationale: Bone marrow transplantation (BMT) is used frequently to study the role of hematopoietic cells in atherosclerosis, but aortic arch lesions are smaller in mice after BMT. Objective: To identify...