Cora Sau Wan Lai
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Explore the profile of Cora Sau Wan Lai including associated specialties, affiliations and a list of published articles.
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19
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814
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Recent Articles
1.
Zheng Q, Huang Y, Mu C, Hu X, Lai C
Adv Sci (Weinh)
. 2024 Oct;
11(44):e2400662.
PMID: 39382074
Sleep stabilizes memories for their consolidation, but how to modify specific fear memory during sleep remains unclear. Here, it is reported that using targeted memory reactivation (TMR) to reactivate prior...
2.
Fok A, Huang Y, So B, Zheng Q, Tse C, Li X, et al.
Cell Rep
. 2024 Mar;
43(3):113906.
PMID: 38451812
Kinesin 1 (KIF5) is one major type of motor protein in neurons, but its members' function in the intact brain remains less studied. Using in vivo two-photon imaging, we find...
3.
Jia G, Sun Y, An P, Wu W, Shen Y, Liu H, et al.
Cereb Cortex
. 2024 Feb;
34(2).
PMID: 38367612
Consequences of perceptual training, such as improvements in discriminative ability, are highly stimulus and task specific. Therefore, most studies on auditory training-induced plasticity in adult brain have focused on the...
4.
Weng M, Hu H, Graus M, Tan D, Gao Y, Ren S, et al.
Sci Adv
. 2023 Aug;
9(34):eadh2501.
PMID: 37611093
Advanced strategies to interconvert cell types provide promising avenues to model cellular pathologies and to develop therapies for neurological disorders. Yet, methods to directly transdifferentiate somatic cells into multipotent induced...
5.
Cheng Y, Tang B, Zhang G, An P, Sun Y, Gao M, et al.
Neuropharmacology
. 2022 Feb;
209:109000.
PMID: 35182575
Hearing disorders, such as abnormal speech perception, are frequently reported in individuals with autism. However, the mechanisms underlying these auditory-associated signature deficits in autism remain largely unknown. In this study,...
6.
Adler A, Lai C, Yang G, Geron E, Bai Y, Gan W
Proc Natl Acad Sci U S A
. 2021 Dec;
118(50).
PMID: 34873044
Changes in synaptic connections are believed to underlie long-term memory storage. Previous studies have suggested that sleep is important for synapse formation after learning, but how sleep is involved in...
7.
Jiang H, Guo A, Chiu A, Li H, Lai C, Lau C
FASEB J
. 2021 Sep;
35(10):e21944.
PMID: 34569087
Information represented by principal neurons in anterior piriform cortex (APC) is regulated by local, recurrent excitation and inhibition, but the circuit mechanisms remain elusive. Two types of layer 2 (L2)...
8.
Huang Y, Jiang H, Zheng Q, Fok A, Li X, Lau C, et al.
Mol Psychiatry
. 2021 Jan;
26(6):2533-2552.
PMID: 33473150
Synaptic deficit-induced excitation and inhibition (E/I) imbalance have been implicated in the pathogenesis of schizophrenia. Using in vivo two-photon microscopy, we examined the dynamic plasticity of dendritic spines of pyramidal...
9.
Zhou Y, Lai C, Bai Y, Li W, Zhao R, Yang G, et al.
Nat Commun
. 2020 Sep;
11(1):4819.
PMID: 32968048
In many parts of the nervous system, experience-dependent refinement of neuronal circuits predominantly involves synapse elimination. The role of sleep in this process remains unknown. We investigated the role of...
10.
Lin L, Lyu Q, Kwan P, Zhao J, Fan R, Chai A, et al.
PLoS Genet
. 2020 Feb;
16(1):e1008587.
PMID: 32004315
Perturbation of synapse development underlies many inherited neurodevelopmental disorders including intellectual disability (ID). Diverse mutations on the human TBC1D24 gene are strongly associated with epilepsy and ID. However, the physiological...