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Cora Sau Wan Lai

Explore the profile of Cora Sau Wan Lai including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 814
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Recent Articles
11.
Zhao J, Fok A, Fan R, Kwan P, Chan H, Lo L, et al.
Elife . 2020 Jan; 9. PMID: 31961321
The kinesin I family of motor proteins are crucial for axonal transport, but their roles in dendritic transport and postsynaptic function are not well-defined. Gene duplication and subsequent diversification give...
12.
Chen K, Zheng Y, Wei J, Ouyang H, Huang X, Zhang F, et al.
Sci Adv . 2019 Jul; 5(7):eaaw1888. PMID: 31281888
Physical exercise improves learning and memory, but little in vivo evidence has been provided to illustrate the molecular mechanisms. Here, we show that chronic treadmill exercise activates the mechanistic target...
13.
Shi D, Huang Y, Lai C, Dong C, Ho L, Li X, et al.
Mol Neurobiol . 2019 Jan; 56(8):5626-5642. PMID: 30659419
Chemotherapy-induced cognitive impairment, also known as "chemobrain," is a common side effect. The purpose of this study was to examine whether ginsenoside Rg1, a ginseng-derived compound, could prevent chemobrain and...
14.
Ng L, Huang Y, Han L, Chang R, Chan Y, Lai C
Transl Psychiatry . 2018 Dec; 8(1):272. PMID: 30531859
Stress is a major risk factor for the onset of many psychiatric diseases. In rodent models, chronic stress induces depression and impairs excitatory neurotransmission. However, little is known about the...
15.
Lai C, Adler A, Gan W
Proc Natl Acad Sci U S A . 2018 Aug; 115(37):9306-9311. PMID: 30150391
Fear conditioning-induced behavioral responses can be extinguished after fear extinction. While fear extinction is generally thought to be a form of new learning, several lines of evidence suggest that neuronal...
16.
Shi D, Huang Y, Lai C, Dong C, Ho L, Wu E, et al.
Mol Neurobiol . 2018 Jul; 56(3):2234-2243. PMID: 30008071
Chemotherapy-induced cognitive impairment, often referred to as "chemobrain," is a common side effect. In this study, mice received three intraperitoneal injections of a combination of docetaxel, adriamycin, and cyclophosphamide (DAC)...
17.
Lai C
Intravital . 2017 Mar; 3(3):e944439. PMID: 28243511
Dendritic spines are the postsynaptic part of most excitatory synapses in the mammalian brain. Recent works have suggested that the structural and functional plasticity of dendritic spines have been associated...
18.
Yang G, Lai C, Cichon J, Ma L, Li W, Gan W
Science . 2014 Jun; 344(6188):1173-8. PMID: 24904169
How sleep helps learning and memory remains unknown. We report in mouse motor cortex that sleep after motor learning promotes the formation of postsynaptic dendritic spines on a subset of...
19.
Lai C, Franke T, Gan W
Nature . 2012 Feb; 483(7387):87-91. PMID: 22343895
It is generally believed that fear extinction is a form of new learning that inhibits rather than erases previously acquired fear memories. Although this view has gained much support from...