Constanze Breithaupt
Overview
Explore the profile of Constanze Breithaupt including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
558
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Recent Articles
1.
Prasad A, Breithaupt C, Nguyen D, Lilie H, Ziegler J, Stubbs M
J Biol Chem
. 2022 Oct;
298(12):102601.
PMID: 36265588
MqnA, the only chorismate dehydratase known so far, catalyzes the initial step in the biosynthesis of menaquinone via the futalosine pathway. Details of the MqnA reaction mechanism remain unclear. Here,...
2.
Spadaro M, Winklmeier S, Beltran E, Macrini C, Hoftberger R, Schuh E, et al.
Ann Neurol
. 2018 Jul;
84(2):315-328.
PMID: 30014603
Objective: Autoantibodies against myelin oligodendrocyte glycoprotein (MOG) occur in a proportion of patients with inflammatory demyelinating diseases of the central nervous system (CNS). We analyzed their pathogenic activity by affinity-purifying...
3.
Spadaro M, Gerdes L, Mayer M, Ertl-Wagner B, Laurent S, Krumbholz M, et al.
Ann Clin Transl Neurol
. 2015 Mar;
2(3):295-301.
PMID: 25815356
We present histological, MRI, and clinical features of an adult patient with relapsing encephalomyelitis and antibodies against myelin oligodendrocyte glycoprotein (MOG). Furthermore, we report molecular details of the recognized epitope...
4.
Structure of the Toll-Spatzle complex, a molecular hub in Drosophila development and innate immunity
Parthier C, Stelter M, Ursel C, Fandrich U, Lilie H, Breithaupt C, et al.
Proc Natl Acad Sci U S A
. 2014 Apr;
111(17):6281-6.
PMID: 24733933
Drosophila Toll receptors are involved in embryonic development and the immune response of adult flies. In both processes, the only known Toll receptor ligand is the human nerve growth factor-like...
5.
Geissler K, Jung M, Riecken L, Sperka T, Cui Y, Schacke S, et al.
Proc Natl Acad Sci U S A
. 2013 Dec;
110(51):20587-92.
PMID: 24297905
Receptor tyrosine kinases participate in several signaling pathways through small G proteins such as Ras (rat sarcoma). An important component in the activation of these G proteins is Son of...
6.
Mayer M, Breithaupt C, Reindl M, Schanda K, Rostasy K, Berger T, et al.
J Immunol
. 2013 Sep;
191(7):3594-604.
PMID: 24014878
Autoantibodies targeting conformationally intact myelin oligodendrocyte glycoprotein (MOG) are found in different inflammatory diseases of the CNS, but their antigenic epitopes have not been mapped. We expressed mutants of MOG...
7.
Stelter M, Fandrich U, Franzke K, Schierhorn A, Breithaupt C, Parthier C, et al.
Biol Chem
. 2013 Jun;
394(8):1091-6.
PMID: 23729564
Drosophila Toll receptors are involved in embryonic development and in the immune response of adult flies. In both processes, the Toll receptor ligand is the NGF-like cystine knot protein Spätzle....
8.
Parthier C, Gorlich S, Jaenecke F, Breithaupt C, Brauer U, Fandrich U, et al.
Angew Chem Int Ed Engl
. 2012 Mar;
51(17):4046-52.
PMID: 22383337
No abstract available.
9.
Breithaupt C, Kurzbauer R, Schaller F, Stintzi A, Schaller A, Huber R, et al.
J Mol Biol
. 2009 Aug;
392(5):1266-77.
PMID: 19660473
12-Oxophytodienoate reductase 3 (OPR3) is a FMN-dependent oxidoreductase that catalyzes the reduction of the cyclopentenone (9S,13S)-12-oxophytodienoate [(9S,13S)-OPDA] to the corresponding cyclopentanone in the biosynthesis of the plant hormone jasmonic acid....
10.
Saleh H, Merkel U, Geissler K, Sperka T, Sechi A, Breithaupt C, et al.
J Mol Biol
. 2008 Dec;
385(4):1015-31.
PMID: 19084535
Ezrin, radixin and moesin are a family of proteins that provide a link between the plasma membrane and the cortical actin cytoskeleton. The regulated targeting of ezrin to the plasma...