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Conor Hennessy

Explore the profile of Conor Hennessy including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 61
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Recent Articles
1.
McCallion O, Cross A, Brook M, Hennessy C, Ferreira R, Trzupek D, et al.
Med . 2024 Dec; :100561. PMID: 39731908
Background: Adoptive transfer of autologous regulatory T cells (Tregs) is a promising therapeutic strategy aimed at enabling immunosuppression minimization following kidney transplantation. In our phase 1 clinical trial of Treg...
2.
Brook M, Hennessy C, Hester J, Hammad S, Alzhrani A, Rombach I, et al.
Transplantation . 2024 Jun; 108(11):2278-2286. PMID: 38845088
Background: The TWO Study (Transplantation Without Overimmunosuppression) aimed to investigate a novel approach to regulatory T-cell (Treg) therapy in renal transplant patients, using a delayed infusion protocol at 6 mo...
3.
Hennessy C, Henry J, Parameswaran G, Brameier D, Kharbanda R, Myerson S
Cureus . 2023 Dec; 15(11):e48297. PMID: 38058336
Recently, both US and European guidelines have predominantly recommended coronary artery bypass grafting (CABG) as the preferred revascularisation method. However, emerging data have raised the possibility of percutaneous coronary intervention...
4.
Hennessy C, Deptula M, Hester J, Issa F
Front Med (Lausanne) . 2023 Feb; 10:1090721. PMID: 36744143
There has been an increased interest in cell based therapies for a range of medical conditions in the last decade. This explosion in novel therapeutics research has led to the...
5.
Hennessy C, Brameier D, Williams M, McVeigh J, de Andres Crespo M, Hoppe S, et al.
Surg Innov . 2022 Mar; 29(5):687-688. PMID: 35341412
No abstract available.
6.
Hennessy C, McKernan D
Cells . 2021 Sep; 10(9). PMID: 34571909
Pattern recognition receptors (PRRs) play a central role in the inflammation that ensues following microbial infection by their recognition of molecular patterns present in invading microorganisms but also following tissue...
7.
Hennessy O, Fowler A, Hennessy C, Brinkman D, Hogan A, Nugent E, et al.
Ir J Med Sci . 2021 Aug; 191(4):1823-1829. PMID: 34453309
Background: The World Health Organisation declared a global pandemic on the 11 March 2020 resulting in implementation of methods to contain viral spread, including curtailment of all elective and non-emergent...
8.
Hennessy C, Lewik G, Cross A, Hester J, Issa F
Fac Rev . 2021 Mar; 10:21. PMID: 33718938
Organ transplantation is a life-saving treatment for end-stage organ failure. However, despite advances in immunosuppression, donor matching, tissue typing, and organ preservation, many organs are still lost each year to...
9.
Hennessy C, OConnell S, Egan L, McKernan D
Immunopharmacol Immunotoxicol . 2019 Sep; 41(5):527-537. PMID: 31505962
Pattern recognition receptors form an essential part of the host defenses against pathogens, in particular in the intestinal epithelium. However, despite their importance relatively little is understood about the regulation...
10.
Hennessy C, McKernan D
Immunol Cell Biol . 2016 Mar; 94(7):631-9. PMID: 26924642
Toll-like receptors (TLRs) are a family of 13 receptors known as pattern-recognition receptors (PRRs) and have a key role in the innate immune response. The TLRs are activated by pathogen-associated...