Collins Karikari
Overview
Explore the profile of Collins Karikari including associated specialties, affiliations and a list of published articles.
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21
Citations
1577
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Recent Articles
1.
Hillion J, Smail S, Di Cello F, Belton A, Shah S, Huso T, et al.
Pancreatology
. 2012 Aug;
12(4):372-9.
PMID: 22898640
Context: Although pancreatic cancer is a common, highly lethal malignancy, the molecular events that enable precursor lesions to become invasive carcinoma remain unclear. We previously reported that the high-mobility group...
2.
Pramanik D, Campbell N, Das S, Gupta S, Chenna V, Bisht S, et al.
Oncotarget
. 2012 Jul;
3(6):640-50.
PMID: 22791660
Acquired chemotherapy resistance is a major contributor to treatment failure in oncology. For example, the efficacy of the common anticancer agent doxorubicin (DOX) is limited by the emergence of multidrug...
3.
Fendrich V, Oh E, Bang S, Karikari C, Ottenhof N, Bisht S, et al.
Neoplasia
. 2011 Oct;
13(10):923-30.
PMID: 22028618
Ligand-dependent activation of the Hedgehog (Hh) signaling pathway has been implicated in both tumor initiation and metastasis of pancreatic ductal adenocarcinoma (PDAC). Prior studies in genetically engineered mouse models (GEMMs)...
4.
Chenna V, Hu C, Pramanik D, Aftab B, Karikari C, Campbell N, et al.
Mol Cancer Ther
. 2011 Oct;
11(1):165-73.
PMID: 22027695
Aberrant activation of the hedgehog (Hh) signaling pathway is one of the most prevalent abnormalities in human cancer. Tumors with cell autonomous Hh activation (e.g., medulloblastomas) can acquire secondary mutations...
5.
Feldmann G, Mishra A, Bisht S, Karikari C, Garrido-Laguna I, Rasheed Z, et al.
Cancer Biol Ther
. 2011 Jul;
12(7):598-609.
PMID: 21768779
Pancreatic cancer is one of the most lethal of human malignancies, and potent therapeutic options are lacking. Inhibition of cell cycle progression through pharmacological blockade of cyclin-dependent kinases (CDK) has...
6.
Zhang Y, Maitra A, Hsieh J, Rudin C, Peacock C, Karikari C, et al.
Cancer Biol Ther
. 2011 Jul;
12(7):617-28.
PMID: 21750403
Purpose: To investigate the frequency of xenotropic murine leukemia virus (MLV) presence in human cell lines established from mouse xenografts and to search for the evidence of horizontal viral spread...
7.
Garrido-Laguna I, Uson M, Rajeshkumar N, Tan A, de Oliveira E, Karikari C, et al.
Clin Cancer Res
. 2011 Jul;
17(17):5793-800.
PMID: 21742805
Purpose: The goal of this study was to evaluate prospectively the engraftment rate, factors influencing engraftment, and predictability of clinical outcome of low-passage xenografts from patients with resectable pancreatic ductal...
8.
Pramanik D, Campbell N, Karikari C, Chivukula R, Kent O, Mendell J, et al.
Mol Cancer Ther
. 2011 May;
10(8):1470-80.
PMID: 21622730
Mis-expression of microRNAs (miRNA) is widespread in human cancers, including in pancreatic cancer. Aberrations of miRNA include overexpression of oncogenic miRs (Onco-miRs) or downregulation of so-called tumor suppressor TSG-miRs. Restitution...
9.
Feldmann G, Karikari C, Dal Molin M, Duringer S, Volkmann P, Bartsch D, et al.
Cancer Biol Ther
. 2011 Apr;
11(11):959-68.
PMID: 21455033
An inactivating germline mutation in BRCA2 is the most common known genetic basis for familial pancreatic cancer (FPC), accounting for 5-10% of inherited cases. A genetically engineered mouse model of...
10.
Hector A, Montgomery E, Karikari C, Canto M, Dunbar K, Wang J, et al.
Cancer Biol Ther
. 2010 Sep;
10(10):1009-18.
PMID: 20818175
Esophageal adenocarcinoma (EAC) arises in the backdrop of reflux-induced metaplastic phenomenon known as Barrett esophagus. The prognosis of advanced EAC is dismal, and there is an urgent need for identifying...