Colin Luo
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Explore the profile of Colin Luo including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
230
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Recent Articles
1.
Sullivan H, Liang Y, Worthington K, Luo C, Gianneschi N, Christman K
Biomacromolecules
. 2023 Sep;
24(11):4695-4704.
PMID: 37695847
Herein, we have developed a drug-loaded matrix metalloproteinase (MMP)-responsive micellar nanoparticle (NP) intended for minimally invasive intravenous injection during the acute phase of myocardial infarction (MI) and prolonged retention in...
2.
Liang Y, Sullivan H, Carrow K, Mesfin J, Korpanty J, Worthington K, et al.
J Am Chem Soc
. 2023 May;
145(20):11185-11194.
PMID: 37184379
Nanoparticles that undergo a localized morphology change to target areas of inflammation have been previously developed but are limited by their lack of biodegradability. In this paper, we describe a...
3.
Spang M, Middleton R, Diaz M, Hunter J, Mesfin J, Banka A, et al.
Nat Biomed Eng
. 2022 Dec;
7(2):94-109.
PMID: 36581694
Decellularized extracellular matrix in the form of patches and locally injected hydrogels has long been used as therapies in animal models of disease. Here we report the safety and feasibility...
4.
Wang R, Mesfin J, Hunter J, Cattaneo P, Guimaraes-Camboa N, Braden R, et al.
Acta Biomater
. 2022 Aug;
152:47-59.
PMID: 36041648
As the native regenerative potential of adult cardiac tissue is limited post-injury, stimulating endogenous repair mechanisms in the mammalian myocardium is a potential goal of regenerative medicine therapeutics. Injection of...
5.
Luong A, Smith D, Tai C, Cotter B, Luo C, Strachan M, et al.
Ultrasound Med Biol
. 2020 Jan;
46(3):690-702.
PMID: 31899038
This study details the development, characterization and non-clinical efficacy of an ultrasound molecular imaging agent intended for molecular imaging of P-selectin in humans. A targeting ligand based on a recently...
6.
Carlini A, Gaetani R, Braden R, Luo C, Christman K, Gianneschi N
Nat Commun
. 2019 Apr;
10(1):1735.
PMID: 30988291
Injectable biopolymer hydrogels have gained attention for use as scaffolds to promote cardiac function and prevent negative left ventricular (LV) remodeling post-myocardial infarction (MI). However, most hydrogels tested in preclinical...
7.
Suarez S, Munoz A, Mitchell A, Braden R, Luo C, Cochran J, et al.
ACS Biomater Sci Eng
. 2018 Jan;
2(2):197-204.
PMID: 29333489
Injectable biomaterials are promising as new therapies to treat myocardial infarction (MI). One useful property of biomaterials is the ability to protect and sustain release of therapeutic payloads. In order...
8.
Nguyen M, Carlini A, Chien M, Sonnenberg S, Luo C, Braden R, et al.
Adv Mater
. 2015 Aug;
27(37):5547-52.
PMID: 26305446
A method for targeting to and retaining intravenously injected nanoparticles at the site of acute myocardial infarction in a rat model is described. Enzyme-responsive peptide-polymer amphiphiles are assembled as spherical...
9.
Kuo D, Licon K, Bandyopadhyay S, Chuang R, Luo C, Catalana J, et al.
Genome Res
. 2010 Oct;
20(12):1672-8.
PMID: 20978140
Transcriptional networks have been shown to evolve very rapidly, prompting questions as to how such changes arise and are tolerated. Recent comparisons of transcriptional networks across species have implicated variations...
10.
Tan K, Feizi H, Luo C, Fan S, Ravasi T, Ideker T
Proc Natl Acad Sci U S A
. 2008 Feb;
105(8):2934-9.
PMID: 18287073
Duplication of genes encoding transcription factors plays an essential role in driving phenotypic variation. Because regulation can occur at multiple levels, it is often difficult to discern how each duplicated...