Clive W Coen
Overview
Explore the profile of Clive W Coen including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
639
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Recent Articles
1.
Garcia Rates S, Garcia-Ayllon M, Falgas N, Brangman S, Esiri M, Coen C, et al.
Alzheimers Dement
. 2024 May;
20(7):5027-5034.
PMID: 38780014
This perspective offers an alternative to the amyloid hypothesis in the etiology of Alzheimer's disease (AD). We review evidence for a novel signaling mechanism based on a little-known peptide, T14....
2.
Greenfield S, Ferrati G, Coen C, Vadisiute A, Molnar Z, Garcia-Rates S, et al.
Int J Mol Sci
. 2022 Nov;
23(21).
PMID: 36361905
The substantia nigra is generally considered to show significant cell loss not only in Parkinson's but also in Alzheimer's disease, conditions that share several neuropathological traits. An interesting feature of...
3.
Greenfield S, Cole G, Coen C, Frautschy S, Singh R, Mekkittikul M, et al.
Alzheimers Dement (N Y)
. 2022 Apr;
8(1):e12274.
PMID: 35415206
Introduction: The neuronal mechanism driving Alzheimer's disease (AD) is incompletely understood. Methods: Immunohistochemistry, pharmacology, biochemistry, and behavioral testing are employed in two pathological contexts-AD and a transgenic mouse model-to investigate...
4.
Coen C, Bennett N, Holmes M, Faulkes C
Adv Exp Med Biol
. 2021 Aug;
1319:59-103.
PMID: 34424513
The African mole-rat family (Bathyergidae) includes the first mammalian species identified as eusocial: naked mole-rats. Comparative studies of eusocial and solitary mole-rat species have identified differences in neuropeptidergic systems that...
5.
Medger K, Bennett N, Chimimba C, Oosthuizen M, Mikkelsen J, Coen C
J Comp Neurol
. 2018 Jul;
526(15):2388-2405.
PMID: 30004584
Of the 18 sub-Saharan elephant-shrew species, only eastern rock elephant-shrews reproduce seasonally throughout their distribution, a process seemingly independent of photoperiod. The present study characterizes gonadal status and location/intensity of...
6.
Samuelsson A, Mullier A, Maicas N, Oosterhuis N, Bae S, Novoselova T, et al.
Proc Natl Acad Sci U S A
. 2016 Oct;
113(43):12298-12303.
PMID: 27791019
Melanocortin-4 receptor (Mc4r)-expressing neurons in the autonomic nervous system, particularly in the paraventricular nucleus of the hypothalamus (PVH), play an essential role in blood pressure (BP) control. Mc4r-deficient (Mc4rKO) mice...
7.
Garcia-Rates S, Morrill P, Tu H, Pottiez G, Badin A, Tormo-Garcia C, et al.
Neuropharmacology
. 2016 Feb;
105:487-499.
PMID: 26867503
The primary cause of Alzheimer's disease is unlikely to be the much studied markers amyloid beta or tau. Their widespread distribution throughout the brain does not account for the specific...
8.
Gugusheff J, Bae S, Rao A, Clarke I, Poston L, Taylor P, et al.
Behav Brain Res
. 2016 Jan;
301:124-31.
PMID: 26718219
Perinatal junk food exposure increases the preference for palatable diets in juvenile and adult rat offspring. Previous studies have implicated reduced sensitivity of the opioid pathway in the programming of...
9.
Coen C
J Endocrinol
. 2015 Jul;
226(2):E3-6.
PMID: 26209092
The brain's unimaginably complex operations are expressed in just two types of output: muscle activity and hormone release. These are the means by which the brain acts beyond its bony...
10.
Coen C, Kalamatianos T, Oosthuizen M, Poorun R, Faulkes C, Bennett N
J Comp Neurol
. 2015 Apr;
523(16):2344-71.
PMID: 25921928
Various aspects of social behavior are influenced by the highly conserved corticotrophin-releasing factor (CRF) family of peptides and receptors in the mammalian telencephalon. This study has mapped and compared the...