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Clinton S Robbins

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Articles 62
Citations 4532
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Recent Articles
1.
Manning A, Tilstra G, Khan A, Couture-Senecal J, Lau Y, Pang J, et al.
Small . 2023 Jun; 19(41):e2302917. PMID: 37312676
Lipid nanoparticles (LNPs) and ribonucleic acid (RNA) technology are highly versatile tools that can be deployed for diagnostic, prophylactic, and therapeutic applications. In this report, supramolecular chemistry concepts are incorporated...
2.
Khan A, Robbins C
Nat Immunol . 2023 Mar; 24(5):743-745. PMID: 36997673
No abstract available.
3.
Hardtner C, Kumar A, Ehlert C, Vico T, Starz C, von Ehr A, et al.
Atherosclerosis . 2023 Mar; 371:1-13. PMID: 36940535
Background And Aims: Atherosclerosis is a systemic and chronic inflammatory disease propagated by monocytes and macrophages. Yet, our knowledge on how transcriptome of these cells evolves in time and space...
4.
Emoto T, Lu J, Sivasubramaniyam T, Maan H, Khan A, Abow A, et al.
Immunity . 2022 May; 55(5):862-878.e8. PMID: 35508166
Macrophage colony stimulating factor-1 (CSF-1) plays a critical role in maintaining myeloid lineage cells. However, congenital global deficiency of CSF-1 (Csf1) causes severe musculoskeletal defects that may indirectly affect hematopoiesis....
5.
Emoto T, Yamamoto H, Yamashita T, Takaya T, Sawada T, Takeda S, et al.
Circulation . 2022 May; 145(18):1434-1436. PMID: 35500048
No abstract available.
6.
Kaufmann E, Khan N, Tran K, Ulndreaj A, Pernet E, Fontes G, et al.
Cell Rep . 2022 Mar; 38(10):110502. PMID: 35235831
Since the vast majority of species solely rely on innate immunity for host defense, it stands to reason that a critical evolutionary trait like immunological memory evolved in this primitive...
7.
Ulndreaj A, Li A, Chen Y, Besla R, Pacheco S, Althagafi M, et al.
Clin Sci (Lond) . 2021 May; 135(10):1295-1309. PMID: 33978148
Objective: Aortic macrophage accumulation is characteristic of the pathogenesis of abdominal aortic aneurysm (AAA) but the mechanisms of macrophage accumulation and their phenotype are poorly understood. Lymphatic vessel endothelial receptor-1...
8.
Sivasubramaniyam T, Yang J, Cheng H, Zyla A, Li A, Besla R, et al.
Sci Rep . 2021 Feb; 11(1):4723. PMID: 33633277
Inflammation is a key contributor to atherosclerosis with macrophages playing a pivotal role through the induction of oxidative stress and cytokine/chemokine secretion. DJ1, an anti-oxidant protein, has shown to paradoxically...
9.
Ikeda J, Scipione C, Hyduk S, Althagafi M, Atif J, Dick S, et al.
Circ Res . 2021 Jan; 128(4):530-543. PMID: 33397122
Rationale: Bone marrow transplantation (BMT) is used frequently to study the role of hematopoietic cells in atherosclerosis, but aortic arch lesions are smaller in mice after BMT. Objective: To identify...
10.
Hardtner C, Kornemann J, Krebs K, Ehlert C, Jander A, Zou J, et al.
Basic Res Cardiol . 2020 Dec; 115(6):78. PMID: 33296022
Statins induce plaque regression characterized by reduced macrophage content in humans, but the underlying mechanisms remain speculative. Studying the translational APOE*3-Leiden.CETP mouse model with a humanized lipoprotein metabolism, we find...