Clifton Dalgard
Overview
Explore the profile of Clifton Dalgard including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
289
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Recent Articles
11.
Gunasekaran T, Reyes-Dumeyer D, Faber K, Goate A, Boeve B, Cruchaga C, et al.
medRxiv
. 2024 Jan;
PMID: 38196599
Background: Few rare variants have been identified in genetic loci from genome wide association studies of Alzheimer's disease (AD), limiting understanding of mechanisms and risk assessment, and genetic counseling. Methods:...
12.
Daley B, Sealover N, Sheffels E, Hughes J, Gerlach D, Hofmann M, et al.
bioRxiv
. 2023 Dec;
PMID: 38106234
Clinical effectiveness of KRAS G12C inhibitors (G12Cis) is limited both by intrinsic and acquired resistance, necessitating the development of combination approaches. We found that targeting proximal receptor tyrosine kinase (RTK)...
13.
Chio A, Moglia C, Canosa A, Manera U, Grassano M, Vasta R, et al.
Neurology
. 2023 May;
101(1):e83-e93.
PMID: 37202167
Background And Objectives: Despite recent advances, it is not clear whether the various genes/genetic variants related to amyotrophic lateral sclerosis (ALS) interact in modifying patients' phenotype. The aim of this...
14.
Slaven J, Wilkerson M, Soltis A, Rittase W, Bradfield D, Bylicky M, et al.
Antioxidants (Basel)
. 2023 Feb;
12(2).
PMID: 36829800
Low dose-rate radiation exposure can occur in medical imaging, as background from environmental or industrial radiation, and is a hazard of space travel. In contrast with high dose-rate radiation exposure...
15.
Zanovello M, Ibanez K, Brown A, Sivakumar P, Bombaci A, Santos L, et al.
Brain
. 2023 Feb;
146(7):2723-2729.
PMID: 36797998
CAG repeat expansions in exon 1 of the AR gene on the X chromosome cause spinal and bulbar muscular atrophy, a male-specific progressive neuromuscular disorder associated with a variety of...
16.
Calvo A, Canosa A, Moglia C, Manera U, Grassano M, Vasta R, et al.
Neurol Genet
. 2022 Oct;
8(6):e200033.
PMID: 36313067
Background And Objectives: To characterize the clinical and cognitive behavioral phenotype and brain F-2-fluoro-2-deoxy-d-glucose-PET (F-FDG-PET) metabolism of patients with amyotrophic lateral sclerosis (ALS) carrying the rs12608932 variant of the gene....
17.
Chio A, Moglia C, Canosa A, Manera U, Grassano M, Vasta R, et al.
J Neurol Neurosurg Psychiatry
. 2022 Aug;
PMID: 36008116
Objective: To detect the clinical characteristics of patients with amyotrophic lateral sclerosis (ALS) carrying an intermediate polyQ number of repeats in a large population-based series of Italian patients with ALS....
18.
Grassano M, Calvo A, Moglia C, Sbaiz L, Brunetti M, Barberis M, et al.
J Neurol Neurosurg Psychiatry
. 2022 Jul;
PMID: 35896380
Background: A genetic diagnosis in Amyotrophic Lateral Sclerosis (ALS) can inform genetic counselling, prognosis and, in the light of incoming gene-targeted therapy, management. However, conventional genetic testing strategies are often...
19.
Glass J, Dewan R, Ding J, Gibbs J, Dalgard C, Keagle P, et al.
Brain
. 2022 May;
145(8):2671-2676.
PMID: 35521889
Intermediate CAG (polyQ) expansions in the gene ataxin-2 (ATXN2) are now recognized as a risk factor for amyotrophic lateral sclerosis. The threshold for increased risk is not yet firmly established,...
20.
Kohaar I, Zhang X, Tan S, Nousome D, Babcock K, Ravindranath L, et al.
Nat Commun
. 2022 Mar;
13(1):1361.
PMID: 35292633
In prostate cancer, emerging data highlight the role of DNA damage repair genes (DDRGs) in aggressive forms of the disease. However, DDRG mutations in African American men are not yet...