Clemens Hermann
Overview
Explore the profile of Clemens Hermann including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
386
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Recent Articles
1.
Hermann C, King C
Oxf Open Immunol
. 2023 Feb;
2(1):iqab015.
PMID: 36845566
Tuberculosis, an infectious disease caused by (Mtb), is a major cause of global morbidity and mortality. The primary barrier to the development of an effective tuberculosis vaccine is our failure...
2.
Okpara M, Hermann C, van der Watt P, Garnett S, Blackburn J, Leaner V
Sci Rep
. 2022 Nov;
12(1):20171.
PMID: 36418423
Karyopherin beta 1 (Kpnβ1) is the principal nuclear importer of cargo proteins and plays a role in many cellular processes. Its expression is upregulated in cancer and essential for cancer...
3.
Hermann C, Karamchand L, Blackburn J, Soares N
J Proteome Res
. 2020 Nov;
20(1):94-109.
PMID: 33140963
The World Health Organization (WHO) estimates that , the most pathogenic mycobacterium species to humans, has infected up to a quarter of the world's population, with the occurrence of multidrug-resistant...
4.
Davids M, Pooran A, Hermann C, Mottay L, Thompson F, Cardenas J, et al.
Am J Respir Crit Care Med
. 2019 Dec;
201(10):1277-1291.
PMID: 31860339
A human model to better understand tuberculosis immunopathogenesis and facilitate vaccine development is urgently needed. We evaluated the feasibility, safety, and immunogenicity of live bacillus Calmette-Guérin (BCG) in a lung-oriented...
5.
Hermann C, Giddey A, Nel A, Soares N, Blackburn J
MethodsX
. 2019 Jan;
5:475-484.
PMID: 30622917
The comprehensive characterisation of the cell wall proteome of mycobacteria is of considerable relevance to both the discovery of new drug targets as well as to the design of new...
6.
Ganief N, Sjouerman J, Albeldas C, Nakedi K, Hermann C, Calder B, et al.
Emerg Microbes Infect
. 2018 Dec;
7(1):212.
PMID: 30546046
Mycobacterium manages to evade the host cell immune system, partially owing to its ability to survive redox stress after macrophage engulfment. Exposure to redox stress has been linked to later...
7.
Tudor Ilca F, Neerincx A, Hermann C, Marcu A, Stevanovic S, Deane J, et al.
Elife
. 2018 Nov;
7.
PMID: 30484775
Tapasin and TAPBPR are known to perform peptide editing on major histocompatibility complex class I (MHC I) molecules; however, the precise molecular mechanism(s) involved in this process remain largely enigmatic....
8.
Hermann C, Giddey A, Nel A, Soares N, Blackburn J
J Proteomics
. 2018 Feb;
191:166-179.
PMID: 29466714
Understanding the cell wall of mycobacteria is crucial for improving drug design or identifying new antigens suitable to vaccination. Yet this remains problematic due to the complexity of the cell...
9.
Neerincx A, Hermann C, Antrobus R, van Hateren A, Cao H, Trautwein N, et al.
Elife
. 2017 Apr;
6.
PMID: 28425917
Recently, we revealed that TAPBPR is a peptide exchange catalyst that is important for optimal peptide selection by MHC class I molecules. Here, we asked whether any other co-factors associate...
10.
Hermann C, van Hateren A, Trautwein N, Neerincx A, Duriez P, Stevanovic S, et al.
Elife
. 2015 Oct;
4.
PMID: 26439010
Our understanding of the antigen presentation pathway has recently been enhanced with the identification that the tapasin-related protein TAPBPR is a second major histocompatibility complex (MHC) class I-specific chaperone. We...