Clayton A Smith
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Explore the profile of Clayton A Smith including associated specialties, affiliations and a list of published articles.
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64
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1305
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Recent Articles
1.
Debnath P, Morin C, Bonn J, Thapaliya S, Smith C, Dillman J, et al.
Hepatol Commun
. 2024 Sep;
8(10).
PMID: 39292183
Background: To determine the effect of stress maneuvers/interventions on ultrasound liver stiffness measurements (LSMs) in patients with Fontan circulation and healthy controls. Methods: In this prospective, IRB-approved study of 10...
2.
Kent A, Gil K, Jones M, Linden B, Purev E, Haverkos B, et al.
Transplant Cell Ther
. 2024 Aug;
PMID: 39154914
Despite the concurrent use of haploidentical cord (HCT) and dual cord (DCT) stem cell transplant approaches for over a decade, there have been few comparisons of their outcomes. Our objective...
3.
Lake K, Colonnetta M, Smith C, Saunders K, Martinez-Algarin K, Mohta S, et al.
Front Cell Dev Biol
. 2024 Jun;
12:1358583.
PMID: 38827528
Breast cancer metastases exhibit many different genetic alterations, including copy number amplifications (CNA). CNA are genetic alterations that are increasingly becoming relevant to breast oncology clinical practice. Here we identify...
4.
Sheth A, Althoff M, Tolison H, Engel K, Amaya M, Krug A, et al.
Cancer Discov
. 2024 May;
14(10):1922-1939.
PMID: 38787341
Acute myeloid leukemia stem cells (LSCs) are uniquely reliant on oxidative phosphorylation (OXPHOS) for survival. Moreover, maintenance of OXPHOS is dependent on BCL-2, creating a therapeutic opportunity to target LSCs...
5.
Sheth A, Engel K, Tolison H, Althoff M, Amaya M, Krug A, et al.
bioRxiv
. 2023 Oct;
PMID: 37873284
We previously reported that acute myeloid leukemia stem cells (LSCs) are uniquely reliant on oxidative phosphorylation (OXPHOS) for survival. Moreover, maintenance of OXPHOS is dependent on BCL2, creating a therapeutic...
6.
Wilson H, Hashemi S, Smith C, Sallee 3rd D, Kim D, Slesnick T
Am J Cardiol
. 2023 Sep;
206:98-100.
PMID: 37690151
No abstract available.
7.
Pei S, Shelton I, Gillen A, Stevens B, Gasparetto M, Wang Y, et al.
Cancer Discov
. 2023 Jun;
13(9):2032-2049.
PMID: 37358260
Significance: These studies identify and characterize a new type of human acute myeloid LSC that is responsible for monocytic disease progression in patients with AML treated with venetoclax-based regimens. Our...
8.
Kent A, Schwartz M, McMahon C, Amaya M, Smith C, Tobin J, et al.
Bone Marrow Transplant
. 2023 May;
58(8):849-854.
PMID: 37185614
Relapse is the most common cause of mortality in acute myeloid leukemia (AML) patients after allogeneic stem cell transplant (SCT). Post-SCT maintenance strategies that prevent relapse are desirable but must...
9.
Pickard S, Armstrong A, Balasubramanian S, Buddhe S, Crum K, Kong G, et al.
J Cardiovasc Comput Tomogr
. 2023 Mar;
17(3):211-219.
PMID: 36868899
Background: To promote the rational use of cardiovascular imaging in patients with congenital heart disease, the American College of Cardiology developed Appropriate Use Criteria (AUC), but its clinical application and...
10.
Lake K, Colonetta M, Smith C, Martinez-Algarin K, Saunders K, Mohta S, et al.
bioRxiv
. 2023 Feb;
PMID: 36778256
Breast cancer metastases exhibit many different genetic alterations, including copy number amplifications. Using publicly available datasets, we identify copy number amplifications in metastatic breast tumor samples and using our organoid-based...