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Claudio Villota

Explore the profile of Claudio Villota including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 13
Citations 401
Followers 0
Related Specialties
Biochemistry
Oncology
General Medicine
Top 10 Co-Authors
Luis O Burzio
Jaime Villegas
Veronica A Burzio
Vincenzo Borgna
Constanza Lopez
Eduardo Landerer
Veronica Silva
Teresa Socias
Lorena Lobos-Gonzalez
Mariela Araya
Published In
J Biol Chem
Oncotarget
Nucleic Acids Res
Pigment Cell Melanoma Res
J Cancer
Affiliations
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Recent Articles
1.
[Oncological Patients' Perception of Received Information: Adaptation and Psychometric Evaluation of the EORTC QLQINFO25 Questionnaire in Chilean Patients]
Corbeaux T, Rivera D, Soza-Ried C, Guerra J, Villota C, Yudin T, et al.
Rev Med Chil . 2024 Oct; 152(3):290-301. PMID: 39450833
Aim: To adapt and assess the psychometric properties of the European Organization for Research and Treatment of Cancer (EORTC) QLQ-INFO25 questionnaire in Chilean patients. Methods And Patients: The EORTC QLQ-INFO25...
2.
Targeting antisense mitochondrial noncoding RNAs induces bladder cancer cell death and inhibition of tumor growth through reduction of survival and invasion factors
Borgna V, Lobos-Gonzalez L, Guevara F, Landerer E, Bendek M, Avila R, et al.
J Cancer . 2020 Mar; 11(7):1780-1791. PMID: 32194789
Knockdown of the antisense noncoding mitochondrial RNAs (ASncmtRNAs) induces apoptotic death of several human tumor cell lines, but not normal cells, supporting a selective therapy against different types of cancer....
3.
Mitochondrial ncRNA targeting induces cell cycle arrest and tumor growth inhibition of MDA-MB-231 breast cancer cells through reduction of key cell cycle progression factors
Fitzpatrick C, Bendek M, Briones M, Farfan N, Silva V, Nardocci G, et al.
Cell Death Dis . 2019 May; 10(6):423. PMID: 31142736
The family of long noncoding mitochondrial RNAs (ncmtRNAs), comprising sense (SncmtRNA), and antisense (ASncmtRNA-1 and ASncmtRNA-2) members, are differentially expressed according to cell proliferative status; SncmtRNA is expressed in all...
4.
HPV-18 E2 protein downregulates antisense noncoding mitochondrial RNA-2, delaying replicative senescence of human keratinocytes
Villota C, Varas-Godoy M, Jeldes E, Campos A, Villegas J, Borgna V, et al.
Aging (Albany NY) . 2019 Jan; 11(1):33-47. PMID: 30595560
Human and mouse cells display a differential expression pattern of a family of mitochondrial noncoding RNAs (ncmtRNAs), according to proliferative status. Normal proliferating and cancer cells express a sense ncmtRNA...
5.
In vivo knockdown of antisense non-coding mitochondrial RNAs by a lentiviral-encoded shRNA inhibits melanoma tumor growth and lung colonization
Varas-Godoy M, Lladser A, Farfan N, Villota C, Villegas J, Tapia J, et al.
Pigment Cell Melanoma Res . 2017 Jul; 31(1):64-72. PMID: 28707763
The family of non-coding mitochondrial RNAs (ncmtRNA) is differentially expressed according to proliferative status. Normal proliferating cells express sense (SncmtRNA) and antisense ncmtRNAs (ASncmtRNAs), whereas tumor cells express SncmtRNA and...
6.
Mitochondrial ASncmtRNA-1 and ASncmtRNA-2 as potent targets to inhibit tumor growth and metastasis in the RenCa murine renal adenocarcinoma model
Borgna V, Villegas J, Burzio V, Belmar S, Araya M, Jeldes E, et al.
Oncotarget . 2017 Jun; 8(27):43692-43708. PMID: 28620146
Knockdown of antisense noncoding mitochondrial RNAs (ASncmtRNAs) induces apoptosis in several human and mouse tumor cell lines, but not normal cells, suggesting this approach for a selective therapy against different...
7.
Targeting antisense mitochondrial ncRNAs inhibits murine melanoma tumor growth and metastasis through reduction in survival and invasion factors
Lobos-Gonzalez L, Silva V, Araya M, Restovic F, Echenique J, Oliveira-Cruz L, et al.
Oncotarget . 2016 Aug; 7(36):58331-58350. PMID: 27507060
We reported that knockdown of the antisense noncoding mitochondrial RNAs (ASncmtRNAs) induces apoptotic death of several human tumor cell lines, but not normal cells, suggesting this approach for selective therapy...
8.
Down-regulation of the antisense mitochondrial non-coding RNAs (ncRNAs) is a unique vulnerability of cancer cells and a potential target for cancer therapy
Vidaurre S, Fitzpatrick C, Burzio V, Briones M, Villota C, Villegas J, et al.
J Biol Chem . 2014 Aug; 289(39):27182-27198. PMID: 25100722
Hallmarks of cancer are fundamental principles involved in cancer progression. We propose an additional generalized hallmark of malignant transformation corresponding to the differential expression of a family of mitochondrial ncRNAs...
9.
Determination of the differential expression of mitochondrial long non-coding RNAs as a noninvasive diagnosis of bladder cancer
Rivas A, Burzio V, Landerer E, Borgna V, Gatica S, Avila R, et al.
BMC Urol . 2012 Dec; 12:37. PMID: 23249382
Background: Bladder cancer is a significant cause of morbidity and mortality with a high recurrence rate. Early detection of bladder cancer is essential in order to remove the tumor, to...
10.
Expression of mitochondrial non-coding RNAs (ncRNAs) is modulated by high risk human papillomavirus (HPV) oncogenes
Villota C, Campos A, Vidaurre S, Oliveira-Cruz L, Boccardo E, Burzio V, et al.
J Biol Chem . 2012 Apr; 287(25):21303-15. PMID: 22539350
The study of RNA and DNA oncogenic viruses has proved invaluable in the discovery of key cellular pathways that are rendered dysfunctional during cancer progression. An example is high risk...