Claudia Nussbaum
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Explore the profile of Claudia Nussbaum including associated specialties, affiliations and a list of published articles.
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38
Citations
659
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Recent Articles
21.
Nussbaum C, Haberer A, Tiefenthaller A, Januszewska K, Chappell D, Brettner F, et al.
J Thorac Cardiovasc Surg
. 2015 Sep;
150(6):1474-81.e1.
PMID: 26395044
Objective: Perturbation of the endothelial glycocalyx is discussed in the pathogenesis of complications related to cardiopulmonary bypass. We evaluated the effects of cardiopulmonary bypass on the microcirculation and the microvascular...
22.
Nussbaum C, Bannenberg S, Keul P, Graler M, Goncalves-de-Albuquerque C, Korhonen H, et al.
Nat Commun
. 2015 Apr;
6:6416.
PMID: 25832730
Sphingosine-1-phosphate (S1P) participates in inflammation; however, its role in leukocyte rolling is still unclear. Here we use intravital microscopy in inflamed mouse cremaster muscle venules and human endothelial cells to...
23.
Bruegger D, Brettner F, Rossberg I, Nussbaum C, Kowalski C, Januszewska K, et al.
Ann Thorac Surg
. 2015 Jan;
99(3):926-31.
PMID: 25601655
Background: There is no doubt today about the existence of the endothelial glycocalyx (EG) and its decisive role in maintaining vascular homeostasis in adult humans. Shedding of the EG has...
24.
Nussbaum C, Cavalcanti Fernandes Heringa A, Mormanova Z, Puchwein-Schwepcke A, Pozza S, Genzel-Boroviczeny O
J Pediatr
. 2013 Dec;
164(3):584-9.e1.
PMID: 24367980
Objective: To evaluate the microcirculation of children with type 1 diabetes mellitus who demonstrate no clinical signs of diabetic microangiopathy for the presence of microvascular alterations and glycocalyx perturbation. Study...
25.
Stachel G, Trenkwalder T, Gotz F, El Aouni C, Muenchmeier N, Pfosser A, et al.
Stem Cells
. 2013 Jun;
31(9):1795-805.
PMID: 23744498
The facilitated recruitment of vascular progenitor cells (VPCs) to ischemic areas might be a therapeutic target for neovascularization and repair. However, efficient and directed attraction of VPCs remains a major...
26.
Sperandio M, Quackenbush E, Sushkova N, Altstatter J, Nussbaum C, Schmid S, et al.
Blood
. 2013 Mar;
121(21):e118-28.
PMID: 23525796
In adult mammals, leukocyte recruitment follows a well-defined cascade of adhesion events enabling leukocytes to leave the circulatory system and transmigrate into tissue. Currently, it is unclear whether leukocyte recruitment...
27.
Jakob S, Pick R, Brechtefeld D, Nussbaum C, Kiefer F, Sperandio M, et al.
Blood
. 2013 Mar;
121(20):4184-94.
PMID: 23460610
Recruitment of polymorphonuclear neutrophils (PMNs) to sites of acute inflammation critically depends on β2 integrins (CD11/CD18). Recently, the mammalian actin-binding protein 1 (mAbp1) was identified as an important adaptor protein...
28.
Nussbaum C, Gloning A, Pruenster M, Frommhold D, Bierschenk S, Genzel-Boroviczeny O, et al.
J Leukoc Biol
. 2012 Dec;
93(2):175-84.
PMID: 23233729
Attenuation of the immune response contributes to the high rate of neonatal infections, particularly in premature infants. Whereas our knowledge of innate immune functions in mature neonates is growing, little...
29.
Nussbaum C, Klinke A, Adam M, Baldus S, Sperandio M
Antioxid Redox Signal
. 2012 Jul;
18(6):692-713.
PMID: 22823200
Significance: The heme-enzyme myeloperoxidase (MPO) is one of the major neutrophil bactericidal proteins and is stored in large amounts inside azurophilic granules of neutrophils. Upon cell activation, MPO is released...
30.
Coordinated roles of ST3Gal-VI and ST3Gal-IV sialyltransferases in the synthesis of selectin ligands
Yang W, Nussbaum C, Grewal P, Marth J, Sperandio M
Blood
. 2012 Jun;
120(5):1015-26.
PMID: 22700726
Binding of selectins to their glycan ligands is a prerequisite for successful leukocyte trafficking. During synthesis and transport through the secretory pathway, selectin ligands are constructed with the participation of...