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Claudia L K Hung

Explore the profile of Claudia L K Hung including associated specialties, affiliations and a list of published articles. Areas
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Citations 44
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Recent Articles
1.
Maiuri T, Hung C, Suart C, Begeja N, Barba-Bazan C, Peng Y, et al.
J Huntingtons Dis . 2021 Feb; 10(1):165-173. PMID: 33579859
The use of genome wide association studies (GWAS) in Huntington's disease (HD) research, driven by unbiased human data analysis, has transformed the focus of new targets that could affect age...
2.
Son S, Bowie L, Maiuri T, Hung C, Desmond C, Xia J, et al.
J Biol Chem . 2018 Dec; 294(6):1915-1923. PMID: 30538129
Huntington's disease (HD) is a neurodegenerative, age-onset disorder caused by a CAG DNA expansion in exon 1 of the gene, resulting in a polyglutamine expansion in the huntingtin protein. Nuclear...
3.
Bowie L, Maiuri T, Alpaugh M, Gabriel M, Arbez N, Galleguillos D, et al.
Proc Natl Acad Sci U S A . 2018 Jul; 115(30):E7081-E7090. PMID: 29987005
The huntingtin N17 domain is a modulator of mutant huntingtin toxicity and is hypophosphorylated in Huntington's disease (HD). We conducted high-content analysis to find compounds that could restore N17 phosphorylation....