Claudia L Edgar
Overview
Explore the profile of Claudia L Edgar including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
114
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Recent Articles
1.
Sharma A, Nair R, Achreja A, Mittal A, Gupta P, Balakrishnan K, et al.
Sci Adv
. 2022 Sep;
8(39):eabq5575.
PMID: 36170375
The connections between metabolic state and therapy resistance in multiple myeloma (MM) are poorly understood. We previously reported that electron transport chain (ETC) suppression promotes sensitivity to the BCL-2 antagonist...
2.
Ronald Funk C, Wang S, Chen K, Waller A, Sharma A, Edgar C, et al.
Blood
. 2022 Jan;
139(4):523-537.
PMID: 35084470
Current limitations in using chimeric antigen receptor T(CART) cells to treat patients with hematological cancers include limited expansion and persistence in vivo that contribute to cancer relapse. Patients with chronic...
3.
Bajpai R, Sharma A, Achreja A, Edgar C, Wei C, Siddiqa A, et al.
Nat Commun
. 2020 Mar;
11(1):1228.
PMID: 32144272
The BCL-2 antagonist venetoclax is highly effective in multiple myeloma (MM) patients exhibiting the 11;14 translocation, the mechanistic basis of which is unknown. In evaluating cellular energetics and metabolism of...