Claudia Catalanotti
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Explore the profile of Claudia Catalanotti including associated specialties, affiliations and a list of published articles.
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15
Citations
517
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Recent Articles
1.
Fang L, Zhu B, Zhao Y, Chen W, Yang Z, Kerrigan L, et al.
Nat Biotechnol
. 2021 Sep;
39(9):1151-1160.
PMID: 34504347
The lack of samples for generating standardized DNA datasets for setting up a sequencing pipeline or benchmarking the performance of different algorithms limits the implementation and uptake of cancer genomics....
2.
Velazquez-Villarreal E, Maheshwari S, Sorenson J, Fiddes I, Kumar V, Yin Y, et al.
Commun Biol
. 2020 Jun;
3(1):318.
PMID: 32587328
We performed shallow single-cell sequencing of genomic DNA across 1475 cells from a cell-line, COLO829, to resolve overall complexity and clonality. This melanoma tumor-line has been previously characterized by multiple...
3.
Andor N, Lau B, Catalanotti C, Sathe A, Kubit M, Chen J, et al.
NAR Genom Bioinform
. 2020 Mar;
2(2):lqaa016.
PMID: 32215369
Cancer cell lines are not homogeneous nor are they static in their genetic state and biological properties. Genetic, transcriptional and phenotypic diversity within cell lines contributes to the lack of...
4.
Marks P, Garcia S, Martinez Barrio A, Belhocine K, Bernate J, Bharadwaj R, et al.
Genome Res
. 2019 Mar;
29(4):635-645.
PMID: 30894395
Large-scale population analyses coupled with advances in technology have demonstrated that the human genome is more diverse than originally thought. To date, this diversity has largely been uncovered using short-read...
5.
Yang W, Wittkopp T, Li X, Warakanont J, Dubini A, Catalanotti C, et al.
Proc Natl Acad Sci U S A
. 2015 Dec;
112(48):14978-83.
PMID: 26627249
Photosynthetic microorganisms typically have multiple isoforms of the electron transfer protein ferredoxin, although we know little about their exact functions. Surprisingly, a Chlamydomonas reinhardtii mutant null for the ferredoxin-5 gene...
6.
Yang W, Catalanotti C, Wittkopp T, Posewitz M, Grossman A
Plant J
. 2015 Mar;
82(3):481-503.
PMID: 25752440
Chlamydomonas reinhardtii is a unicellular, soil-dwelling (and aquatic) green alga that has significant metabolic flexibility for balancing redox equivalents and generating ATP when it experiences hypoxic/anoxic conditions. The diversity of...
7.
Yang W, Catalanotti C, DAdamo S, Wittkopp T, Ingram-Smith C, Mackinder L, et al.
Plant Cell
. 2014 Nov;
26(11):4499-518.
PMID: 25381350
Chlamydomonas reinhardtii insertion mutants disrupted for genes encoding acetate kinases (EC 2.7.2.1) (ACK1 and ACK2) and a phosphate acetyltransferase (EC 2.3.1.8) (PAT2, but not PAT1) were isolated to characterize fermentative...
8.
Catalanotti C, Yang W, Posewitz M, Grossman A
Front Plant Sci
. 2013 Jun;
4:150.
PMID: 23734158
Fermentation or anoxic metabolism allows unicellular organisms to colonize environments that become anoxic. Free-living unicellular algae capable of a photoautotrophic lifestyle can also use a range of metabolic circuitry associated...
9.
Heinnickel M, Alric J, Wittkopp T, Yang W, Catalanotti C, Dent R, et al.
J Biol Chem
. 2013 Jan;
288(10):7024-36.
PMID: 23303190
Based on previous comparative genomic analyses, a set of nearly 600 polypeptides was identified that is present in green algae and flowering and nonflowering plants but is not present (or...
10.
Catalanotti C, Dubini A, Subramanian V, Yang W, Magneschi L, Mus F, et al.
Plant Cell
. 2012 Feb;
24(2):692-707.
PMID: 22353371
Chlamydomonas reinhardtii, a unicellular green alga, often experiences hypoxic/anoxic soil conditions that activate fermentation metabolism. We isolated three Chlamydomonas mutants disrupted for the pyruvate formate lyase (PFL1) gene; the encoded...