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Clara Ruiz-Fernandez

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Articles 23
Citations 493
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Recent Articles
11.
Gonzalez-Rodriguez M, Ruiz-Fernandez C, Cordero-Barreal A, Ait Eldjoudi D, Pino J, Farrag Y, et al.
Drug Discov Today . 2022 Sep; 27(11):103352. PMID: 36099964
Adipokines are the principal mediators in adipose signaling. Nevertheless, besides their role in energy storage, these molecules can be produced by other cells, such as immune cells or chondrocytes. Given...
12.
Ruiz-Fernandez C, Gonzalez-Rodriguez M, Abella V, Francisco V, Cordero-Barreal A, Ait Eldjoudi D, et al.
Lab Invest . 2022 Apr; 102(9):989-999. PMID: 35484291
Wnt-1 inducible signaling pathway protein 2 (WISP-2/CCN5) is a recently identified adipokine that has been described as an important mediator of canonical Wnt activation in adipogenic precursor cells. In osteoarthritis...
13.
Ait Eldjoudi D, Cordero Barreal A, Gonzalez-Rodriguez M, Ruiz-Fernandez C, Farrag Y, Farrag M, et al.
Int J Mol Sci . 2022 Mar; 23(5). PMID: 35270000
White adipose tissue (WAT) is a specialized tissue whose main function is lipid synthesis and triglyceride storage. It is now considered as an active organ secreting a plethora of hormones...
14.
Ait Eldjoudi D, Ruiz-Fernandez C, Gonzalez-Rodriguez M, Ait Atmane S, Cordero-Barreal A, Farrag Y, et al.
Phytother Res . 2022 Feb; 36(3):1372-1385. PMID: 35194856
Nigella species have been widely used in traditional medicine. The aim of this study was to evaluate the antiinflammatory and analgesic potentials of Nigella orientalis L. seeds fixed oil (NOO)....
15.
Ruiz-Fernandez C, Gonzalez-Rodriguez M, Francisco V, Rajab I, Gomez R, Conde J, et al.
Lab Invest . 2021 Mar; 101(12):1550-1560. PMID: 33767361
C-reactive protein (CRP) is an acute-phase protein that is used as an established biomarker to follow disease severity and progression in a plethora of inflammatory diseases. However, its pathophysiologic mechanisms...
16.
Cordero-Barreal A, Gonzalez-Rodriguez M, Ruiz-Fernandez C, Ait Eldjoudi D, AbdElHafez Y, Lago F, et al.
Int J Mol Sci . 2021 Mar; 22(5). PMID: 33673730
Since its discovery in 1994, leptin has been considered as an adipokine with pleiotropic effects. In this review, we summarize the actual information about the impact of this hormone on...
17.
Francisco V, Ruiz-Fernandez C, Gonzalez-Rodriguez M, Cordero-Barreal A, Pino J, Vinuela J, et al.
J Ethnopharmacol . 2021 Feb; 272:113932. PMID: 33609728
Ethnopharmacological Relevance: Virola oleifera (Schott) A.C. Smith, Myristicaceae, has been widely used in traditional medicine in Brazil to treat rheumatic pain, joint tumours, skin diseases, halitosis, bronchial asthma, haemorrhoids, and...
18.
Gonzalez-Rodriguez M, Ruiz-Fernandez C, Francisco V, Ait Eldjoudi D, AbdElHafez Y, Cordero-Barreal A, et al.
Molecules . 2021 Feb; 26(4). PMID: 33546469
is the largest genus of Myristicaceae in America, comprising about 60 species of medium-sized trees geographically spread from Mexico to southern Brazil. The plant species of this genus have been...
19.
Pirozzi C, Lama A, Annunziata C, Cavaliere G, Ruiz-Fernandez C, Monnolo A, et al.
Antioxidants (Basel) . 2020 Dec; 9(12). PMID: 33265944
Lines of evidence have shown the embryogenic and transgenerational impact of bisphenol A (BPA), an endocrine-disrupting chemical, on immune-metabolic alterations, inflammation, and oxidative stress, while BPA toxic effects in adult...
20.
Conde J, Ruiz-Fernandez C, Francisco V, Scotece M, Gomez R, Lago F, et al.
Cartilage . 2020 Jun; 13(2_suppl):925S-934S. PMID: 32532182
Objective: Osteoarthritis (OA) is an age-related biomechanical and low-grade inflammometabolic disease of the joints and one of the costliest and disabling forms of arthritis. Studies on matrix-degrading enzymes such as...