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Clara Espitia

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Articles 51
Citations 521
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Recent Articles
1.
Carrero J, Espinoza B, Huerta L, Silva-Miranda M, Guzman-Gutierrez S, Dorazco-Gonzalez A, et al.
Pharmaceuticals (Basel) . 2024 Jul; 17(7). PMID: 39065807
The need for new drugs to treat human infections is a global health concern. Diseases like tuberculosis, trypanosomiasis, amoebiasis, and AIDS remain significant problems, especially in developing countries like Mexico....
2.
Martinez-Sotelo J, Vallecillo A, Parada C, Segura E, Campuzano J, Silva-Miranda M, et al.
Curr Microbiol . 2024 May; 81(7):197. PMID: 38816607
Identifying and evaluating potential vaccine candidates has become one of the main objectives to combat tuberculosis. Among them, mannosylated Apa antigen from Mycobacterium tuberculosis and the non-mannosylated protein expressed in...
3.
Munoz-Bucio A, Arellano-Reynoso B, Sangari F, Sieira R, Thebault P, Espitia C, et al.
Arch Microbiol . 2024 May; 206(6):285. PMID: 38816572
Intracellular pathogens like Brucella face challenges during the intraphagocytic adaptation phase, where the modulation of gene expression plays an essential role in taking advantage of stressors to persist inside the...
4.
Juarez-Mercado K, Gomez-Hernandez M, Salinas-Trujano J, Cordova-Bahena L, Espitia C, Perez-Tapia S, et al.
Pharmaceuticals (Basel) . 2024 Feb; 17(2). PMID: 38399455
SARS-CoV-2 Main Protease (Mpro) is an enzyme that cleaves viral polyproteins translated from the viral genome, which is critical for viral replication. Mpro is a target for anti-SARS-CoV-2 drug development....
5.
Zaa C, Espitia C, Reyes-Barrera K, An Z, Velasco-Velazquez M
Biomolecules . 2023 Nov; 13(11). PMID: 38002267
COVID-19 patients can exhibit a wide range of clinical manifestations affecting various organs and systems. Neurological symptoms have been reported in COVID-19 patients, both during the acute phase of the...
6.
Nino-Padilla E, Espitia C, Velazquez C, Alday E, Silva-Campa E, Burgara-Estrella A, et al.
ACS Omega . 2023 Nov; 8(43):40665-40676. PMID: 37929145
The aim of this study was to evaluate the potential antibiofilm activity of () compounds over BCG ( BCG) as a model for (). We evaluated the antibiofilm activity as...
7.
Vicente-Fermin O, Zenteno E, Ramos-Martinez I, Espitia C, Sanchez-Betancourt J, Huerta L
Pathogens . 2022 Dec; 11(12). PMID: 36558852
-acetylneuraminic acid linked to galactose by α2,6 and α2,3 linkages (Siaα2,6 and Siaα2,3) is expressed on glycoconjugates of animal tissues, where it performs multiple biological functions. In addition, these types...
8.
Guzman-Gutierrez S, Reyes-Chilpa R, Gonzalez-Diego L, Silva-Miranda M, Lopez-Caamal A, Garcia-Cruz K, et al.
J Ethnopharmacol . 2022 Oct; 301:115778. PMID: 36202165
Ethnopharmacological Relevance: Several medicinal plants, including the endemic herb Cirsum ehrenbergii (Asteraceae), have been documented in manuscripts, medical and botanical books written in Mexico since the XVI century until the...
9.
Paredes-Gonzalez I, Aparicio-Trejo O, Ramos-Espinosa O, Lopez-Torres M, Maya-Hoyos M, Mendoza-Trujillo M, et al.
Exp Lung Res . 2022 Sep; 48(9-10):251-265. PMID: 36102603
During the early and progressive (late) stages of murine experimental pulmonary tuberculosis, the differential activation of macrophages contributes to disease development by controlling bacterial growth and immune regulation. Mycobacterial proteins...
10.
Carrero J, Curay-Herrera V, Chacon-Nino L, Krengel F, Guzman-Gutierrez S, Silva-Miranda M, et al.
Planta Med . 2022 Mar; 89(2):148-157. PMID: 35338475
Plants of species have several pharmacological activities including antimicrobial effects. Amoebiasis continues to be a public health problem, with increasing evidence of resistance to metronidazole. In this study, we assessed...