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Clara Crescioli

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Citations 1158
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Recent Articles
1.
Mennitti C, Farina G, Imperatore A, De Fonzo G, Gentile A, La Civita E, et al.
Biomolecules . 2024 Nov; 14(11). PMID: 39595594
Physical activity highly impacts the neuroendocrine system and hormonal secretion. Numerous variables, both those related to the individual, including genetics, age, sex, biological rhythms, nutritional status, level of training, intake...
2.
Crescioli C, Paronetto M
Cells . 2024 Oct; 13(20. PMID: 39451238
Growing evidence suggests that neuroinflammation is not just a consequence of neurodegeneration in pathologies such as Alzheimer's disease, Parkinson's disease, Huntington's disease or Amyotrophic lateral sclerosis, but it is rather...
3.
Paronetto M, Crescioli C
Front Endocrinol (Lausanne) . 2024 Oct; 15:1461642. PMID: 39355618
The phosphodiesterases type 5 (PDE5) are catalytic enzymes converting the second messenger cyclic guanosine monophosphate (cGMP) to 5' GMP. While intracellular cGMP reduction is associated with several detrimental effects, cGMP...
4.
Spinelli F, Berti R, Farina G, Ceccarelli F, Conti F, Crescioli C
Autoimmun Rev . 2023 Aug; 22(10):103412. PMID: 37597604
Systemic Lupus Erythematosus (SLE) is a multisystemic autoimmune disorder characterized by flares-ups/remissions with a complex clinical picture related to disease severity and organ/tissue injury, which, if left untreated, may result...
5.
Fantini C, Corinaldesi C, Lenzi A, Migliaccio S, Crescioli C
Int J Mol Sci . 2023 Mar; 24(5). PMID: 36901976
Aging can be seen as a physiological progression of biomolecular damage and the accumulation of defective cellular components, which trigger and amplify the process, toward whole-body function weakening. Senescence initiates...
6.
Ghinassi B, Di Baldassarre A, Crescioli C
Biomolecules . 2022 Dec; 12(12). PMID: 36551178
Although cardiovascular diseases (CVD) are the leading cause of non-communicable diseases-dependent death worldwide, their effects are still largely underestimated in women [...].
7.
Crescioli C
Front Immunol . 2022 Oct; 13:954994. PMID: 36211340
Vitamin D exerts important extra-skeletal effects, exhibiting an exquisite immune regulatory ability, affecting both innate and adaptive immune responses through the modulation of immunocyte function and signaling. Remarkably, the immune...
8.
Colasanti T, Stefanantoni K, Fantini C, Corinaldesi C, Vasile M, Marampon F, et al.
Int J Mol Sci . 2022 Sep; 23(17). PMID: 36077548
The prostacyclin analogue iloprost is used to treat vascular alterations and digital ulcers, the early derangements manifesting in systemic sclerosis (SSc), an autoimmune disease leading to skin and organ fibrosis....
9.
Giannattasio S, Citarella A, Trocchianesi S, Filardi T, Morano S, Lenzi A, et al.
Front Mol Biosci . 2022 Jun; 9:879522. PMID: 35712355
The antidiabetic sodium-glucose cotransporter type 2 inhibitor (SGLT2i) empagliflozin efficiently reduces heart failure (HF) hospitalization and cardiovascular death in type 2 diabetes (T2D). Empagliflozin-cardioprotection likely includes anti-inflammatory effects, regardless glucose...
10.
Migliaccio S, Bimonte V, Besharat Z, Sabato C, Lenzi A, Crescioli C, et al.
Biomolecules . 2022 Jan; 12(1). PMID: 35053192
The number of aged individuals is increasing worldwide, rendering essential the comprehension of pathophysiological mechanisms of age-related alterations, which could facilitate the development of interventions contributing to "successful aging" and...