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How Does Physical Activity Modulate Hormone Responses?

Abstract

Physical activity highly impacts the neuroendocrine system and hormonal secretion. Numerous variables, both those related to the individual, including genetics, age, sex, biological rhythms, nutritional status, level of training, intake of drugs or supplements, and previous or current pathologies, and those related to the physical activity in terms of type, intensity, and duration of exercise, or environmental conditions can shape the hormonal response to physical exercise. The aim of this review is to provide an overview of the effects of physical exercise on hormonal levels in the human body, focusing on changes in concentrations of hormones such as cortisol, testosterone, and insulin in response to different types and intensities of physical activity. Regular monitoring of hormonal responses in athletes could be a potential tool to design individual training programs and prevent overtraining syndrome.

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References
1.
Cortez M, Torgan C, Brozinick Jr J, Ivy J . Insulin resistance of obese Zucker rats exercise trained at two different intensities. Am J Physiol. 1991; 261(5 Pt 1):E613-9. DOI: 10.1152/ajpendo.1991.261.5.E613. View

2.
Grasso D, Corsetti R, Lanteri P, Di Bernardo C, Colombini A, Graziani R . Bone-muscle unit activity, salivary steroid hormones profile, and physical effort over a 3-week stage race. Scand J Med Sci Sports. 2014; 25(1):70-80. DOI: 10.1111/sms.12147. View

3.
Botcazou M, Gratas-Delamarche A, Allain S, Jacob C, Bentue-Ferrer D, Delamarche P . [Influence of menstrual cycle phase on catecholamine response to sprint exercise in the woman]. Appl Physiol Nutr Metab. 2006; 31(5):604-11. DOI: 10.1139/h06-038. View

4.
Sellami M, Bragazzi N, Slimani M, Hayes L, Jabbour G, De Giorgio A . The Effect of Exercise on Glucoregulatory Hormones: A Countermeasure to Human Aging: Insights from a Comprehensive Review of the Literature. Int J Environ Res Public Health. 2019; 16(10). PMC: 6572009. DOI: 10.3390/ijerph16101709. View

5.
Maya J, Misra M . The female athlete triad: review of current literature. Curr Opin Endocrinol Diabetes Obes. 2021; 29(1):44-51. PMC: 8702454. DOI: 10.1097/MED.0000000000000690. View