Ciriana Orabona
Overview
Explore the profile of Ciriana Orabona including associated specialties, affiliations and a list of published articles.
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Articles
87
Citations
4791
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Recent Articles
1.
Lema Fernandez A, Nardelli C, Pierini V, Crescenzi B, Pellanera F, Matteucci C, et al.
Genes Chromosomes Cancer
. 2024 Nov;
63(11):e70013.
PMID: 39604137
Jumping translocations (JT) are rare cytogenetic abnormalities associated with progression in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). Typically, a tri-tetra-somic 1q chromosome is translocated to two or more...
2.
Suvieri C, Mondanelli G, Orabona C, Pallotta M, Panfili E, Rossini S, et al.
Cells
. 2024 Jul;
13(13.
PMID: 38994942
Small synthetic oligodeoxynucleotides (ODNs) can mimic microbial nucleic acids by interacting with receptor systems and promoting immunostimulatory activities. Nevertheless, some ODNs can act differently on the plasmacytoid dendritic cell (pDC)...
3.
Rossini S, Ambrosino S, Volpi C, Belladonna M, Pallotta M, Panfili E, et al.
Front Immunol
. 2024 Feb;
15:1346686.
PMID: 38333210
The tryptophan-degrading enzyme indoleamine 2,3-dioxygenase 1 (IDO1) is a plastic immune checkpoint molecule that potently orchestrates immune responses within the tumor microenvironment (TME). As a heme-containing protein, IDO1 catalyzes the...
4.
Suvieri C, De Marchis F, Mandarano M, Ambrosino S, Rossini S, Mondanelli G, et al.
Int J Mol Sci
. 2023 Nov;
24(22).
PMID: 38003426
Indoleamine 2,3-dioxygenase 2 (IDO2) is a paralog of Indoleamine 2,3-dioxygenase 1 (IDO1), a tryptophan-degrading enzyme producing immunomodulatory molecules. However, the two proteins are unlikely to carry out the same functions....
5.
Volpi C, Van den Eynde B, Orabona C
Front Immunol
. 2023 Aug;
14:1263384.
PMID: 37638027
No abstract available.
6.
Rossini S, Gargaro M, Scalisi G, Bianconi E, Ambrosino S, Panfili E, et al.
Elife
. 2023 Jun;
12.
PMID: 37387273
Src is a protein tyrosine kinase commonly activated downstream of transmembrane receptors and plays key roles in cell growth, migration, and survival signaling pathways. In conventional dendritic cells (cDCs), Src...
7.
Panfili E, Mondanelli G, Orabona C, Gargaro M, Volpi C, Belladonna M, et al.
Front Immunol
. 2023 May;
14:1134551.
PMID: 37122718
Indoleamine 2,3-dioxygenase 1 (IDO1) is a tryptophan metabolizing enzyme chronically activated in many cancer patients and its expression and activity correlate with a poor prognosis. In fact, it acts as...
8.
Stincardini C, Pariano M, DOnofrio F, Renga G, Orecchini E, Orabona C, et al.
PNAS Nexus
. 2023 Mar;
2(3):pgad036.
PMID: 36896128
The environmental light/dark cycle has left its mark on the body's physiological functions to condition not only our inner biology, but also the interaction with external cues. In this scenario,...
9.
Proietti E, Pauwels R, de Vries A, Orecchini E, Volpi C, Orabona C, et al.
Int J Tryptophan Res
. 2023 Feb;
16:11786469231153109.
PMID: 36798536
Background And Aims: Indoleamine 2,3 dioxygenase-1 (IDO1), a key enzyme in tryptophan metabolism, is strongly up-regulated both in human inflammatory bowel disease (IBD) and animal models of colitis, however its...
10.
Franzago M, Orecchini E, Porreca A, Mondanelli G, Orabona C, Ragione L, et al.
Nutrients
. 2023 Jan;
15(2).
PMID: 36678277
Background: The incidence of eating disorders (EDs), serious mental and physical conditions characterized by a disturbance in eating or eating-related behaviors, has increased steadily. The present study aims to develop...