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Chun-Feng D Hou

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Articles 3
Citations 53
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Recent Articles
1.
Swanson N, Hou C, Cingolani G
Microorganisms . 2022 Mar; 10(3). PMID: 35336080
Bacterial viruses (or bacteriophages) have developed formidable ways to deliver their genetic information inside bacteria, overcoming the complexity of the bacterial-cell envelope. In short-tailed phages of the superfamily, genome ejection...
2.
Hou C, Liu J, Collyer C, Mitic N, Pedroso M, Schenk G, et al.
Sci Rep . 2017 Jan; 7:40357. PMID: 28074907
Metallo-β-lactamases (MBLs) with activity towards a broad-spectrum of β-lactam antibiotics have become a major threat to public health, not least due to their ability to rapidly adapt their substrate preference....
3.
Moustakim M, Clark P, Trulli L, Fuentes de Arriba A, Ehebauer M, Chaikuad A, et al.
Angew Chem Int Ed Engl . 2016 Dec; 56(3):827-831. PMID: 27966810
The p300/CBP-associated factor (PCAF) and related GCN5 bromodomain-containing lysine acetyl transferases are members of subfamily I of the bromodomain phylogenetic tree. Iterative cycles of rational inhibitor design and biophysical characterization...