Chui-Yoke Chin
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Explore the profile of Chui-Yoke Chin including associated specialties, affiliations and a list of published articles.
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13
Citations
292
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Recent Articles
1.
Thapa M, Kumari A, Chin C, Choby J, Jin F, Bogati B, et al.
bioRxiv
. 2023 Sep;
PMID: 37693595
The gut-brain axis, a bidirectional signaling network between the intestine and the central nervous system, is crucial to the regulation of host physiology and inflammation. Recent advances suggest a strong...
2.
Chin C, Zhao J, Llewellyn A, Golovliov I, Sjostedt A, Zhou P, et al.
Cell Rep
. 2021 Jun;
35(11):109247.
PMID: 34133919
The outer membrane protects Gram-negative bacteria from the host environment. Lipopolysaccharide (LPS), a major outer membrane constituent, has distinct components (lipid A, core, O-antigen) generated by specialized pathways. In this...
3.
Tipton K, Chin C, Farokhyfar M, Weiss D, Rather P
Antimicrob Agents Chemother
. 2018 Oct;
62(12).
PMID: 30297362
strain AB5075 forms two cell types distinguished by their opaque (VIR-O) or translucent (AV-T) colonies. VIR-O cells possess a thicker capsule and are more resistant to a variety of stressors...
4.
Chin C, Gregg K, Napier B, Ernst R, Weiss D
Antimicrob Agents Chemother
. 2015 Oct;
59(12):7911-4.
PMID: 26459891
Emerging resistance to "last-resort" polymyxin antibiotics in Gram-negative bacteria is a significant threat to public health. We identified the Acinetobacter baumannii NaxD deacetylase as a critical mediator of lipid A...
5.
Chin C, Hara Y, Ghazali A, Yap S, Kong C, Wong Y, et al.
BMC Genomics
. 2015 Jun;
16:471.
PMID: 26092034
Background: Chronic bacterial infections occur as a result of the infecting pathogen's ability to live within a biofilm, hence escaping the detrimental effects of antibiotics and the immune defense system....
6.
Feng Y, Chin C, Chakravartty V, Gao R, Crispell E, Weiss D, et al.
mBio
. 2015 Jun;
6(3):e00591.
PMID: 26060274
Unlabelled: The physiological function of biotin requires biotin protein ligase activity in order to attach the coenzyme to its cognate proteins, which are enzymes involved in central metabolism. The model...
7.
Sampson T, Napier B, Schroeder M, Louwen R, Zhao J, Chin C, et al.
Proc Natl Acad Sci U S A
. 2014 Jul;
111(30):11163-8.
PMID: 25024199
Clustered, regularly interspaced, short palindromic repeats-CRISPR associated (CRISPR-Cas) systems defend bacteria against foreign nucleic acids, such as during bacteriophage infection and transformation, processes which cause envelope stress. It is unclear...
8.
Lee S, Wong R, Chin C, Lim T, Eng S, Kong C, et al.
Proc Natl Acad Sci U S A
. 2013 Aug;
110(37):15067-72.
PMID: 23980181
Burkholderia pseudomallei is a Gram-negative soil bacterium that infects both humans and animals. Although cell culture studies have revealed significant insights into factors contributing to virulence and host defense, the...
9.
Hara Y, Chin C, Mohamed R, Puthucheary S, Nathan S
BMC Infect Dis
. 2013 Apr;
13:165.
PMID: 23556548
Background: Burkholderia pseudomallei, the causative agent of melioidosis, is endemic to Southeast Asia and northern Australia. Clinical manifestations of disease are diverse, ranging from chronic infection to acute septicaemia. The...
10.
Chin C, Tan S, Nathan S
Front Cell Infect Microbiol
. 2012 Aug;
2:85.
PMID: 22919676
Burkholderia pseudomallei is resistant to a diverse group of antimicrobials including third generation cephalosporins whilst quinolones and aminoglycosides have no reliable effect. As therapeutic options are limited, development of more...