Chuanjie Zhang
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Explore the profile of Chuanjie Zhang including associated specialties, affiliations and a list of published articles.
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49
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583
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Recent Articles
1.
Zhang C, Ding J, Lim K, Zhou W, Miao W, Wu S, et al.
Cancer Res
. 2025 Feb;
PMID: 39903850
Ferroptosis inducers have shown therapeutic potential in prostate cancer (PCa), but tumor heterogeneity poses a barrier to their efficacy. Distinguishing the regulators orchestrating metabolic crosstalk between cancer cells could shed...
2.
Wang H, Wu Z, Cui D, Bian L, Zheng Z, Zhu J, et al.
Sci Transl Med
. 2025 Jan;
17(782):eadl6432.
PMID: 39841806
Chimeric antigen receptor (CAR)-T cell therapies have revolutionized the landscape of cancer treatment, in particular in the context of hematologic malignancies. However, for solid tumors that lack tumor-specific antigens, CAR-T...
3.
Jin J, Luo J, Jin X, Lim K, He Y, Ding J, et al.
Cancer Res
. 2024 Nov;
85(4):675-691.
PMID: 39589780
Fumarate hydratase (FH) deficiency causes hereditary leiomyomatosis and renal cell carcinoma (RCC). FH-deficient tumors lack effective therapeutic options. Here, we utilized an epigenetic-focused single-guide RNA library to elucidate potential drug...
4.
Zhang C, Yuan Y, Zhang S, Yan N, Zhao Y, Lu L, et al.
Biochem Biophys Res Commun
. 2024 Sep;
733:150623.
PMID: 39255619
After prolonged space operations, astronauts showed maladaptive atrophy within mostly left-ventricular myocardium, resulting in cardiac dysfunction. However, the mechanism of cardiac dysfunction under microgravity conditions is unclear, and the relevant...
5.
Shen J, Liu L, Yang Y, Zhou M, Xu S, Zhang W, et al.
Cureus
. 2024 Aug;
16(7):e65393.
PMID: 39188438
Autism spectrum disorder (ASD), a heterogeneous group of neurodevelopmental disorders, is characterized by social impairment and repetitive and stereotypic behaviors. Because of the lack of approved laboratory diagnostic markers and...
6.
Zhao Y, Ji G, Zhou S, Cai S, Li K, Zhang W, et al.
iScience
. 2024 May;
27(6):109917.
PMID: 38812544
During space travel, microgravity leads to disturbances in cognitive function, while the underlying mechanism is still unclear. Simulated microgravity mice showed neuronal age-like changes in the hippocampus of our study....
7.
Cheng J, Liu H, Shen Y, Ding J, He H, Mao S, et al.
Transl Oncol
. 2024 May;
45:101987.
PMID: 38743986
Background: Bevacizumab resistance poses barriers to targeted therapy in clear cell renal cell carcinoma (ccRCC). Whether there exist epigenetic targets that modulate bevacizumab sensitivity in ccRCC remains indefinite. The focus...
8.
Zhou S, Li X, Liang F, Ji G, Lv K, Yuan Y, et al.
Int J Mol Sci
. 2024 May;
25(9).
PMID: 38732079
Long-term spaceflight is known to induce disruptions in circadian rhythms, which are driven by a central pacemaker located in the suprachiasmatic nucleus (SCN) of the hypothalamus, but the underlying molecular...
9.
Chen Y, Weng X, Zhang C, Wang S, Wu X, Cheng B
PeerJ
. 2024 Apr;
12:e17222.
PMID: 38650654
Targeting tumor angiogenesis is an important approach in advanced tumor therapy. Here we investigated the effect of the suppressor of variegation 3-9 homolog 1 (SUV39H1) on tumor angiogenesis in oral...
10.
Bai L, Gao J, Zhang P, Lin S, Zhang C
Int Immunopharmacol
. 2024 Apr;
132:111983.
PMID: 38593504
Developing biomimetic nanoparticles without off-target side-effects remains a major challenge in spinal cord injury (SCI) immunotherapy. In this paper, we have conducted a drug carrier which is biocompatible macrophages-exocytosed exosome-biomimetic...