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Chuan-Chih Hsu

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Articles 87
Citations 2141
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Recent Articles
11.
Lin Y, Xu M, Hsu C, Damei F, Lee H, Tsai W, et al.
Nat Commun . 2023 Sep; 14(1):5755. PMID: 37716995
The diversification of effector function, driven by a co-evolutionary arms race, enables pathogens to establish compatible interactions with hosts. Structurally conserved plant pathogenesis-related PR-1 and PR-1-like (PR-1L) proteins are involved...
12.
Chen C, Tsai C, Lin M, Lin S, Hsu C
Anal Chem . 2023 Aug; 95(33):12232-12239. PMID: 37552764
Plant phosphoproteomics provides a global view of phosphorylation-mediated signaling in plants; however, it demands high-throughput methods with sensitive detection and accurate quantification. Despite the widespread use of protein precipitation for...
13.
Li X, Zhu P, Chen Y, Huang L, Wang D, Newton D, et al.
Front Plant Sci . 2023 Jun; 14:1171957. PMID: 37324680
To sustain normal growth and allow rapid responses to environmental cues, plants alter the plasma membrane protein composition under different conditions presumably by regulation of delivery, stability, and internalization. Exocytosis...
14.
Bi Y, Shrestha R, Zhang Z, Hsu C, Reyes A, Karunadasa S, et al.
Plant Cell . 2023 Feb; 35(5):1318-1333. PMID: 36739885
The recent discovery of SPINDLY (SPY)-catalyzed protein O-fucosylation revealed a novel mechanism for regulating nucleocytoplasmic protein functions in plants. Genetic evidence indicates the important roles of SPY in diverse developmental...
15.
Kim T, Park C, Hsu C, Kim Y, Ko Y, Zhang Z, et al.
Plant Cell . 2023 Jan; 35(3):975-993. PMID: 36660928
Elucidating enzyme-substrate relationships in posttranslational modification (PTM) networks is crucial for understanding signal transduction pathways but is technically difficult because enzyme-substrate interactions tend to be transient. Here, we demonstrate that...
16.
Tsai C, Wang Y, Hsu C, Kitata R, Chu R, Velickovic M, et al.
Commun Biol . 2023 Jan; 6(1):70. PMID: 36653408
Effective phosphoproteome of nanoscale sample analysis remains a daunting task, primarily due to significant sample loss associated with non-specific surface adsorption during enrichment of low stoichiometric phosphopeptide. We develop a...
17.
Velez-Bermudez I, Jain D, Ravindran A, Chen C, Hsu C, Schmidt W
Methods Mol Biol . 2022 Nov; 2581:309-319. PMID: 36413327
Mass spectrometry-based proteomics provide a powerful tool for plant research, allowing global detection of steady-state levels of proteins under a given experimental setup. Here, we provide an optimized protocol for...
18.
Czosseck A, Chen M, Nguyen H, Meeson A, Hsu C, Chen C, et al.
J Control Release . 2022 Nov; 352:879-892. PMID: 36370875
Ischemic diseases including myocardial infarction (MI) and limb ischemia are some of the greatest causes of morbidity and mortality worldwide. Cell therapy is a potential treatment but is usually limited...
19.
Zhu P, Wu X, Zhang R, Hsu C, Zhang Z, Tao W
J Proteome Res . 2022 Sep; 21(10):2515-2525. PMID: 36103635
Protein phosphatases play an essential role in normal cell physiology and the development of diseases such as cancer. The innate challenges associated with studying protein phosphatases have limited our understanding...
20.
Chong L, Hsu C, Zhu Y
J Exp Bot . 2022 Aug; 73(19):6547-6557. PMID: 35959917
Abiotic stresses have significant impacts on crop yield and quality. Even though significant efforts during the past decade have been devoted to uncovering the core signaling pathways associated with the...