Christopher S Ward
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Explore the profile of Christopher S Ward including associated specialties, affiliations and a list of published articles.
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1188
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Recent Articles
1.
Hanna A, Chang T, Ho K, Yee R, Walker W, Agha N, et al.
J Gen Physiol
. 2024 Dec;
157(1).
PMID: 39661086
Dilated cardiomyopathy (DCM) is a highly prevalent and genetically heterogeneous condition that results in decreased contractility and impaired cardiac function. The FK506-binding protein FKBP12 has been implicated in regulating the...
2.
Chang Y, Lusk S, Chang A, Ward C, Ray R
Elife
. 2024 Sep;
12.
PMID: 39287624
Central noradrenergic (NA) neurons are key constituents of the respiratory homeostatic network. NA dysfunction is implicated in several developmental respiratory disorders including Congenital Central Hyperventilation Syndrome (CCHS), Sudden Infant Death...
3.
Spielmann N, Miller G, Oprea T, Hsu C, Fobo G, Frishman G, et al.
Nat Cardiovasc Res
. 2024 Aug;
1(2):157-173.
PMID: 39195995
Clinical presentation of congenital heart disease is heterogeneous, making identification of the disease-causing genes and their genetic pathways and mechanisms of action challenging. By using in vivo electrocardiography, transthoracic echocardiography...
4.
Rana S, Canfield J, Ward C, Sprague J
Sci Rep
. 2024 Jun;
14(1):14485.
PMID: 38914648
Hyperthermia induced by phenethylamines, such as 3,4-methylenedioxymethamphetamine (MDMA), can lead to life-threatening complications and death. Activation of the sympathetic nervous system and subsequent release of norepinephrine and activation of uncoupling...
5.
Brown K, Barker K, Wagner R, Ward C, Sitoki L, Njiru J, et al.
Environ Microbiol Rep
. 2024 Jun;
16(3):e13297.
PMID: 38885952
The Winam Gulf (Kenya) is frequently impaired by cyanobacterial harmful algal blooms (cHABs) due to inadequate wastewater treatment and excess agricultural nutrient input. While phytoplankton in Lake Victoria have been...
6.
Wagner R, Neudeck M, Heath A, Barker K, Brown K, Buchholz S, et al.
Harmful Algae
. 2024 Jun;
136:102656.
PMID: 38876531
Sandusky Bay is the drowned mouth of the Sandusky River in the southwestern portion of Lake Erie. The bay is a popular recreation location and a regional source for drinking...
7.
Brown K, Ward C, Bullerjahn G
Microbiol Resour Announc
. 2024 Feb;
13(3):e0120523.
PMID: 38376339
Metagenome-assembled genomes were generated for two xenic cyanobacterial strains collected from aquatic sources in Kenya and sequenced by NovaSeq S4. Here, we report the classification and genome statistics of WG22...
8.
Lusk S, Ward C, Chang A, Twitchell-Heyne A, Fattig S, Allen G, et al.
J Physiol
. 2023 Oct;
601(21):4767-4806.
PMID: 37786382
Comprehensive and accurate analysis of respiratory and metabolic data is crucial to modelling congenital, pathogenic and degenerative diseases converging on autonomic control failure. A lack of tools for high-throughput analysis...
9.
Lee C, Jung S, Yee R, Agha N, Hong J, Chang T, et al.
Commun Biol
. 2023 Sep;
6(1):942.
PMID: 37709832
Here we show that striated muscle preferentially expressed protein kinase α (Spegα) maintains cardiac function in hearts with Spegβ deficiency. Speg is required for stability of excitation-contraction coupling (ECC) complexes...
10.
Oestereicher M, Wotton J, Ayabe S, Bou About G, Cheng T, Choi J, et al.
Mamm Genome
. 2023 Jun;
34(2):180-199.
PMID: 37294348
Reference ranges provide a powerful tool for diagnostic decision-making in clinical medicine and are enormously valuable for understanding normality in pre-clinical scientific research that uses in vivo models. As yet,...