Christopher S Henry
Overview
Explore the profile of Christopher S Henry including associated specialties, affiliations and a list of published articles.
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77
Citations
5117
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Recent Articles
11.
Jeffryes J, Lerma-Ortiz C, Liu F, Golubev A, Niehaus T, Elbadawi-Sidhu M, et al.
Metab Eng
. 2021 Dec;
69:302-312.
PMID: 34958914
Spontaneous reactions between metabolites are often neglected in favor of emphasizing enzyme-catalyzed chemistry because spontaneous reaction rates are assumed to be insignificant under physiological conditions. However, synthetic biology and engineering...
12.
Bathe U, Leong B, McCarty D, Henry C, Abraham P, Wilson M, et al.
Biochemistry
. 2021 Nov;
60(47):3555-3565.
PMID: 34729986
Enzymes have life spans. Analysis of life spans, i.e., lifetime totals of catalytic turnovers, suggests that nonsurvivable collateral chemical damage from the very reactions that enzymes catalyze is a common...
13.
Rubinstein R, Borton M, Zhou H, Shaffer M, Hoyt D, Stegen J, et al.
Bioinformatics
. 2021 Nov;
38(3):778-784.
PMID: 34726691
Motivation: Nutrient and contaminant behavior in the subsurface are governed by multiple coupled hydrobiogeochemical processes which occur across different temporal and spatial scales. Accurate description of macroscopic system behavior requires...
14.
Allen B, Gupta N, Edirisinghe J, Faria J, Henry C
Methods Mol Biol
. 2021 Oct;
2349:291-320.
PMID: 34719000
The DOE Systems Biology Knowledgebase (KBase) platform offers a range of powerful tools for the reconstruction, refinement, and analysis of genome-scale metabolic models built from microbial isolate genomes. In this...
15.
van der Lelie D, Oka A, Taghavi S, Umeno J, Fan T, Merrell K, et al.
Nat Commun
. 2021 May;
12(1):3105.
PMID: 34050144
Environmental factors, mucosal permeability and defective immunoregulation drive overactive immunity to a subset of resident intestinal bacteria that mediate multiple inflammatory conditions. GUT-103 and GUT-108, live biotherapeutic products rationally designed...
16.
Joshi R, McNaughton A, Thomas D, Henry C, Canon S, McCue L, et al.
ACS Omega
. 2021 Apr;
6(14):9948-9959.
PMID: 33869975
Thermodynamics plays a crucial role in regulating the metabolic processes in all living organisms. Accurate determination of biochemical and biophysical properties is important to understand, analyze, and synthetically design such...
17.
Nayfach S, Roux S, Seshadri R, Udwary D, Varghese N, Schulz F, et al.
Nat Biotechnol
. 2021 Apr;
39(4):521.
PMID: 33795890
No abstract available.
18.
Hanson A, McCarty D, Henry C, Xian X, Joshi J, Patterson J, et al.
Proc Natl Acad Sci U S A
. 2021 Mar;
118(13).
PMID: 33753504
Metabolic engineering uses enzymes as parts to build biosystems for specified tasks. Although a part's working life and failure modes are key engineering performance indicators, this is not yet so...
19.
Nayfach S, Roux S, Seshadri R, Udwary D, Varghese N, Schulz F, et al.
Nat Biotechnol
. 2020 Nov;
39(4):520.
PMID: 33208936
No abstract available.
20.
Seaver S, Liu F, Zhang Q, Jeffryes J, Faria J, Edirisinghe J, et al.
Nucleic Acids Res
. 2020 Nov;
49(D1):D1555.
PMID: 33179751
No abstract available.