Christopher S Franklin
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Explore the profile of Christopher S Franklin including associated specialties, affiliations and a list of published articles.
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24
Citations
4862
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Recent Articles
1.
Steinthorsdottir V, McGinnis R, Williams N, Stefansdottir L, Thorleifsson G, Shooter S, et al.
Nat Commun
. 2020 Nov;
11(1):5976.
PMID: 33239696
Preeclampsia is a serious complication of pregnancy, affecting both maternal and fetal health. In genome-wide association meta-analysis of European and Central Asian mothers, we identify sequence variants that associate with...
2.
Munn-Chernoff M, Johnson E, Chou Y, Coleman J, Thornton L, Walters R, et al.
Addict Biol
. 2020 Feb;
26(1):e12880.
PMID: 32064741
Eating disorders and substance use disorders frequently co-occur. Twin studies reveal shared genetic variance between liabilities to eating disorders and substance use, with the strongest associations between symptoms of bulimia...
3.
Watson H, Yilmaz Z, Thornton L, Hubel C, Coleman J, Gaspar H, et al.
Nat Genet
. 2019 Jul;
51(8):1207-1214.
PMID: 31308545
Characterized primarily by a low body-mass index, anorexia nervosa is a complex and serious illness, affecting 0.9-4% of women and 0.3% of men, with twin-based heritability estimates of 50-60%. Mortality...
4.
Iotchkova V, Huang J, Morris J, Jain D, Barbieri C, Walter K, et al.
Nat Genet
. 2018 Nov;
50(12):1752.
PMID: 30390057
In the version of the article published, the surname of author Aaron Isaacs is misspelled as Issacs.
5.
Diogo D, Tian C, Franklin C, Alanne-Kinnunen M, March M, Spencer C, et al.
Nat Commun
. 2018 Oct;
9(1):4285.
PMID: 30327483
Phenome-wide association studies (PheWAS) have been proposed as a possible aid in drug development through elucidating mechanisms of action, identifying alternative indications, or predicting adverse drug events (ADEs). Here, we...
6.
Iotchkova V, Huang J, Morris J, Jain D, Barbieri C, Walter K, et al.
Nat Genet
. 2016 Sep;
48(11):1303-1312.
PMID: 27668658
Large-scale whole-genome sequence data sets offer novel opportunities to identify genetic variation underlying human traits. Here we apply genotype imputation based on whole-genome sequence data from the UK10K and 1000...
7.
Roberts C, Franklin C, Makalo P, Joof H, Sarr I, Mahdi O, et al.
Sci Rep
. 2015 Dec;
5:17447.
PMID: 26616738
Chlamydia trachomatis causes both trachoma and sexually transmitted infections. These diseases have similar pathology and potentially similar genetic predisposing factors. We aimed to identify polymorphisms and pathways associated with pathological...
8.
Huckins L, Boraska V, Franklin C, Floyd J, Southam L, Sullivan P, et al.
Eur J Hum Genet
. 2014 Feb;
22(10):1190-200.
PMID: 24549058
The Wellcome Trust Case Control Consortium 3 anorexia nervosa genome-wide association scan includes 2907 cases from 15 different populations of European origin genotyped on the Illumina 670K chip. We compared...
9.
Boraska V, Day-Williams A, Franklin C, Elliott K, Panoutsopoulou K, Tachmazidou I, et al.
PLoS One
. 2012 Apr;
7(3):e31369.
PMID: 22479309
Brachial circumference (BC), also known as upper arm or mid arm circumference, can be used as an indicator of muscle mass and fat tissue, which are distributed differently in men...
10.
Dastani Z, Hivert M, Timpson N, Perry J, Yuan X, Scott R, et al.
PLoS Genet
. 2012 Apr;
8(3):e1002607.
PMID: 22479202
Circulating levels of adiponectin, a hormone produced predominantly by adipocytes, are highly heritable and are inversely associated with type 2 diabetes mellitus (T2D) and other metabolic traits. We conducted a...