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Christopher R Reynolds

Explore the profile of Christopher R Reynolds including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 160
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Recent Articles
1.
Markova E, Shaw R, Reynolds C
Eng Biol . 2023 Mar; 6(4):82-90. PMID: 36968340
This article presents a discussion of the process of precision fermentation (PF), describing the history of the space, the expected 70% growth over the next 5 years, various applications of...
2.
Rothberg M, Peak T, Reynolds C, Hemal A
Transl Androl Urol . 2020 May; 9(2):879-886. PMID: 32420203
Background: Previous reports on positive surgical margin (PSM) after robot-assisted partial nephrectomy (RAPN) have reached inconsistent conclusions as to the impact of a PSM on oncologic outcomes. We sought to...
3.
Rothberg M, Paulucci D, Okhawere K, Reynolds C, Badani K, Abaza R, et al.
J Endourol . 2020 Jan; 34(3):304-311. PMID: 31931607
To determine the effect of positive surgical margins (PSMs) on oncologic outcomes following robot-assisted partial nephrectomy (RAPN) and to identify factors that increase the likelihood of adverse oncologic outcomes. A...
4.
Reynolds C, Islam S, Sternberg M
J Mol Biol . 2018 Feb; 430(15):2244-2248. PMID: 29391170
EzMol is a molecular visualization Web server in the form of a software wizard, located at http://www.sbg.bio.ic.ac.uk/ezmol/. It is designed for easy and rapid image manipulation and display of protein...
5.
Reynolds C, Delto J, Paulucci D, Weinstein C, Badani K, Eun D, et al.
BJU Int . 2017 Jul; 120(6):842-847. PMID: 28710786
Objective: To compare perioperative and functional outcomes of patients with cT1a or cT1b renal masses undergoing robotic partial nephrectomy (RPN) in a large multi-institutional study PATIENTS AND METHODS: The present...
6.
Sundriyal S, Moniot S, Mahmud Z, Yao S, Di Fruscia P, Reynolds C, et al.
J Med Chem . 2017 Jan; 60(5):1928-1945. PMID: 28135086
Sirtuins (SIRTs) are NAD-dependent deacylases, known to be involved in a variety of pathophysiological processes and thus remain promising therapeutic targets for further validation. Previously, we reported a novel thienopyrimidinone...
7.
Reynolds C, Muggleton S, Sternberg M
Mol Inform . 2015 Nov; 34(9):615-625. PMID: 26583052
The use of virtual screening has become increasingly central to the drug development pipeline, with ligand-based virtual screening used to screen databases of compounds to predict their bioactivity against a...
8.
Di Fruscia P, Zacharioudakis E, Liu C, Moniot S, Laohasinnarong S, Khongkow M, et al.
ChemMedChem . 2014 Nov; 10(1):69-82. PMID: 25395356
Sirtuins, NAD(+) -dependent histone deacetylases (HDACs), have recently emerged as potential therapeutic targets for the treatment of a variety of diseases. The discovery of potent and isoform-selective inhibitors of this...
9.
Reynolds C, Amini A, Muggleton S, Sternberg M
J Phys Chem B . 2012 Mar; 116(23):6732-9. PMID: 22380596
The Investigational Novel Drug Discovery by Example (INDDEx) package has been developed to find active compounds by linking activity to chemical substructure and to guide the process of further drug...