Christopher Plaisier
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Explore the profile of Christopher Plaisier including associated specialties, affiliations and a list of published articles.
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12
Citations
472
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Recent Articles
1.
Huang H, Wang T, Rousseau J, Orlando M, Mungaray M, Michaud C, et al.
Biomaterials
. 2024 Feb;
306:122505.
PMID: 38359507
Atherosclerosis, a chronic inflammatory disease, is the primary cause of myocardial infarction and ischemic stroke. Recent studies have demonstrated that dysregulation of yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding...
2.
Huang H, Wang T, Rousseau J, Mungaray M, Michaud C, Plaisier C, et al.
bioRxiv
. 2023 May;
PMID: 37163067
Atherosclerosis, characterized by the buildup of lipid-rich plaque on the vessel wall, is the primary cause of myocardial infarction and ischemic stroke. Recent studies have demonstrated that dysregulation of yes-associated...
3.
Adjei-Sowah E, OConnor S, Veldhuizen J, Lo Cascio C, Plaisier C, Mehta S, et al.
Adv Sci (Weinh)
. 2022 May;
9(21):e2201436.
PMID: 35619544
The perivascular niche (PVN) is a glioblastoma tumor microenvironment (TME) that serves as a safe haven for glioma stem cells (GSCs), and acts as a reservoir that inevitably leads to...
4.
Velazquez J, LeGraw R, Moghadam F, Tan Y, Kilbourne J, Maggiore J, et al.
Cell Syst
. 2020 Dec;
12(1):41-55.e11.
PMID: 33290741
Pluripotent stem cell (PSC)-derived organoids have emerged as novel multicellular models of human tissue development but display immature phenotypes, aberrant tissue fates, and a limited subset of cells. Here, we...
5.
Eshima J, Ong S, Davis T, Miranda C, Krishnamurthy D, Nachtsheim A, et al.
J Chromatogr B Analyt Technol Biomed Life Sci
. 2019 May;
1121:48-57.
PMID: 31108321
Urinary metabolomics offers a non-invasive means of obtaining information about the system-wide biological health of a patient. Untargeted metabolomics approaches using one-dimensional gas chromatography (GC) are limited due to the...
6.
Zhang L, Singh A, Plaisier C, Pruett N, Ripley R, Schrump D, et al.
Transl Oncol
. 2019 May;
12(6):859-870.
PMID: 31054476
Therapies against malignant pleural mesothelioma (MPM) have yielded disappointing results, in part, because pathologic mechanisms remain obscure. In searching for rational molecular targets, we identified metadherin (MTDH), a multifunctional gene...
7.
Rothchild A, Sissons J, Shafiani S, Plaisier C, Min D, Mai D, et al.
Proc Natl Acad Sci U S A
. 2016 Sep;
113(41):E6172-E6181.
PMID: 27681624
The regulation of host-pathogen interactions during Mycobacterium tuberculosis (Mtb) infection remains unresolved. MicroRNAs (miRNAs) are important regulators of the immune system, and so we used a systems biology approach to...
8.
Presson A, Sobel E, Pajukanta P, Plaisier C, Weeks D, Aberg K, et al.
BMC Bioinformatics
. 2008 Jul;
9:317.
PMID: 18644149
Background: Correctly merged data sets that have been independently genotyped can increase statistical power in linkage and association studies. However, alleles from microsatellite data sets genotyped with different experimental protocols...
9.
Mar-Heyming R, Miyazaki M, Weissglas-Volkov D, Kolaitis N, Sadaat N, Plaisier C, et al.
Arterioscler Thromb Vasc Biol
. 2008 Mar;
28(6):1193-9.
PMID: 18340007
Objective: Stearoyl-CoA desaturase 1 (SCD1) is the rate-limiting enzyme involved in the synthesis of monounsaturated fatty acids, and in mice SCD1 activity is associated with plasma triglyceride levels. We used...
10.
Ghazalpour A, Doss S, Zhang B, Wang S, Plaisier C, Castellanos R, et al.
PLoS Genet
. 2006 Aug;
2(8):e130.
PMID: 16934000
Systems biology approaches that are based on the genetics of gene expression have been fruitful in identifying genetic regulatory loci related to complex traits. We use microarray and genetic marker...