Christopher M Sturgeon
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Explore the profile of Christopher M Sturgeon including associated specialties, affiliations and a list of published articles.
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Articles
31
Citations
1052
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Recent Articles
1.
Sturgeon C, Sturgeon C, Papapetrou E, Papapetrou E, McKinney-Freeman S, McKinney-Fridman S
Exp Hematol
. 2025 Jan;
143:104713.
PMID: 39756786
No abstract available.
2.
Sturgeon C, Wagenblast E, Izzo F, Papapetrou E
Blood Cancer Discov
. 2024 Dec;
6(2):94-109.
PMID: 39652739
In recent years, remarkable technological advances have illuminated aspects of the pathogenesis of myeloid malignancies-yet outcomes for patients with these devastating diseases have not significantly improved. We posit that a...
3.
Luff S, Fernandez N, Sturgeon C, Ditadi A
Exp Hematol
. 2024 Jul;
138:104587.
PMID: 39074529
A diverse array of protocols have been established for the directed differentiation of human pluripotent stem cells (hPSCs) into a variety of cell types, including blood cells, for modeling development...
4.
Scarfo R, Randolph L, Abou Alezz M, El Khoury M, Gersch A, Li Z, et al.
Nat Cell Biol
. 2024 Apr;
26(5):719-730.
PMID: 38594587
During embryonic development, blood cells emerge from specialized endothelial cells, named haemogenic endothelial cells (HECs). As HECs are rare and only transiently found in early developing embryos, it remains difficult...
5.
Collins T, Laranjeira A, Kong T, Fulbright M, Fisher D, Sturgeon C, et al.
Exp Hematol
. 2024 Feb;
132:104178.
PMID: 38340948
Myeloproliferative neoplasms (MPNs) are driven by hyperactivation of JAK-STAT signaling but can demonstrate skewed hematopoiesis upon acquisition of additional somatic mutations. Here, using primary MPN samples and engineered embryonic stem...
6.
Ghersi J, Baldissera G, Hintzen J, Luff S, Cheng S, Xia I, et al.
Nat Cell Biol
. 2023 Jul;
25(8):1135-1145.
PMID: 37460694
Definitive haematopoietic stem and progenitor cells (HSPCs) generate erythroid, lymphoid and myeloid lineages. HSPCs are produced in the embryo via transdifferentiation of haemogenic endothelial cells in the aorta-gonad-mesonephros (AGM). HSPCs...
7.
8.
Creamer J, Luff S, Yu H, Sturgeon C
Stem Cell Res
. 2022 May;
62:102808.
PMID: 35569347
To achieve efficient, reproducible differentiation of human pluripotent stem cells (hPSCs) towards specific hematopoietic cell-types, a comprehensive understanding of the necessary cell signaling and developmental trajectories involved is required. Previous...
9.
Luff S, Creamer J, Valsoni S, Dege C, Scarfo R, Dacunto A, et al.
Nat Cell Biol
. 2022 Apr;
24(5):616-624.
PMID: 35484246
The generation of haematopoietic stem cells (HSCs) from human pluripotent stem cells (hPSCs) is a major goal for regenerative medicine. During embryonic development, HSCs derive from haemogenic endothelium (HE) in...
10.
Bredemeyer A, Amrute J, Koenig A, Idol R, He L, Luff S, et al.
Development
. 2022 Feb;
149(8).
PMID: 35178561
Tissue-resident macrophages are increasingly recognized as important determinants of organ homeostasis, tissue repair, remodeling and regeneration. Although the ontogeny and function of tissue-resident macrophages has been identified as distinct from...