Christopher L German
Overview
Explore the profile of Christopher L German including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
417
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Recent Articles
1.
Magee C, German C, Siripathane Y, Curtis P, Anderson D, Wilkins D, et al.
J Pharmacol Exp Ther
. 2020 May;
374(2):273-282.
PMID: 32385092
Methylenedioxypyrovalerone (MDPV) is an abused synthetic cathinone, commonly referred to as a "bath salt." Because the dopamine (DA) transporter (DAT) and vesicular monoamine transporter-2 (VMAT-2) are key regulators of both...
2.
German C, Gudheti M, Fleckenstein A, Jorgensen E
Methods Mol Biol
. 2017 Sep;
1663:153-162.
PMID: 28924666
Localization microscopy techniques-such as photoactivation localization microscopy (PALM), fluorescent PALM (FPALM), ground state depletion (GSD), and stochastic optical reconstruction microscopy (STORM)-provide the highest precision for single-molecule localization currently available. However,...
3.
Fricks-Gleason A, German C, Hoonakker A, Friend D, Ganesh K, Carver A, et al.
Synapse
. 2016 Jan;
70(4):139-46.
PMID: 26799527
Preclinical studies demonstrate that repeated, high-dose methamphetamine administrations rapidly decrease plasmalemmal dopamine uptake, which may contribute to aberrant dopamine accumulation, reactive species generation, and long-term dopaminergic deficits. The present study...
4.
German C, Baladi M, McFadden L, Hanson G, Fleckenstein A
Pharmacol Rev
. 2015 Sep;
67(4):1005-24.
PMID: 26408528
Dopamine (DA) plays a well recognized role in a variety of physiologic functions such as movement, cognition, mood, and reward. Consequently, many human disorders are due, in part, to dysfunctional...
5.
German C, Alburges M, Hoonakker A, Fleckenstein A, Hanson G
Synapse
. 2014 Aug;
68(12):634-640.
PMID: 25155699
Mephedrone (4-methymethcathinone) is a synthetic cathinone designer drug that disrupts central nervous system (CNS) dopamine (DA) signaling. Numerous central neuropeptide systems reciprocally interact with dopaminergic neurons to provide regulatory counterbalance,...
6.
German C, Hoonakker A, Fleckenstein A, Hanson G
J Neurochem
. 2014 Apr;
130(3):402-7.
PMID: 24678634
Mephedrone (4-methylmethcathinone) is a synthetic cathinone designer drug that alters pre-synaptic dopamine (DA) activity like many psychostimulants. However, little is known about the post-synaptic dopaminergic impacts of mephedrone. The neuropeptide...
7.
German C, Fleckenstein A, Hanson G
Life Sci
. 2013 Aug;
97(1):2-8.
PMID: 23911668
Synthetic cathinones are an emerging class of designer drugs abused for psychostimulant and hallucinogenic effects similar to cocaine, methylenedioxymethamphetamine (MDMA), or other amphetamines. Abuse of synthetic cathinones, frequently included in...
8.
German C, Hanson G, Fleckenstein A
J Neurochem
. 2012 Jul;
123(2):288-97.
PMID: 22804716
Amphetamine (AMPH) and methamphetamine (METH) alter dopamine transporter (DAT) function. In vitro heterologous cell line and synaptosome studies demonstrate AMPH-induced DAT internalization, implicating relocalization in reduced DAT uptake following drug...
9.
Hadlock G, Webb K, McFadden L, Chu P, Ellis J, Allen S, et al.
J Pharmacol Exp Ther
. 2011 Aug;
339(2):530-6.
PMID: 21810934
The designer stimulant 4-methylmethcathinone (mephedrone) is among the most popular of the derivatives of the naturally occurring psychostimulant cathinone. Mephedrone has been readily available for legal purchase both online and...
10.
German C, Sauer B, Howe C
Exp Cell Res
. 2011 May;
317(14):1955-69.
PMID: 21619877
Endocytic trafficking plays an important role in signal transduction. Signal transducer and activator of transcription 3 (STAT3) and mitogen-activate protein kinase (MAPK) have both been localized to endosomal structures and...