Christopher J Flaim
Overview
Explore the profile of Christopher J Flaim including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
485
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Recent Articles
1.
Depelsenaire A, Meliga S, McNeilly C, Pearson F, Coffey J, Haigh O, et al.
J Invest Dermatol
. 2014 Apr;
134(9):2361-2370.
PMID: 24714201
Vaccines delivered to the skin by microneedles-with and without adjuvants-have increased immunogenicity with lower doses than standard vaccine delivery techniques such as intramuscular or intradermal injection. However, the mechanisms underlying...
2.
Chen A, McNeilly C, Liu A, Flaim C, Cuttle L, Kendall M, et al.
Burns
. 2011 Apr;
37(6):1001-9.
PMID: 21501931
High-resolution, high-contrast, three-dimensional images of live cell and tissue architecture can be obtained using second harmonic generation (SHG), which comprises non-absorptive frequency changes in an excitation laser line. SHG does...
3.
Xu X, Cowley S, Flaim C, James W, Seymour L, Cui Z
Biotechnol Prog
. 2010 Jan;
26(3):827-37.
PMID: 20077485
Human embryonic stem (hES) cells have enormous potential for clinical applications. However, one major challenge is to achieve high cell recovery rate after cryopreservation. Understanding how the conventional cryopreservation protocol...
4.
Xu X, Cowley S, Flaim C, James W, Seymour L, Cui Z
Biotechnol Prog
. 2009 Dec;
26(3):781-8.
PMID: 20014103
Due to widespread applications of human embryonic stem (hES) cells, it is essential to establish effective protocols for cryopreservation and subsequent culture of hES cells to improve cell recovery. We...
5.
Flaim C, Teng D, Chien S, Bhatia S
Stem Cells Dev
. 2008 Feb;
17(1):29-39.
PMID: 18271698
Extracellular matrix (ECM) and growth factor signaling networks are known to interact in a complex manner. Therefore, reductionist approaches that test the cellular response to individual ECM components and growth...
6.
Flaim C, Chien S, Bhatia S
Nat Methods
. 2005 Mar;
2(2):119-25.
PMID: 15782209
We present an extracellular matrix (ECM) microarray platform for the culture of patterned cells atop combinatorial matrix mixtures. This platform enables the study of differentiation in response to a multitude...