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Christopher J Destache

Explore the profile of Christopher J Destache including associated specialties, affiliations and a list of published articles. Areas
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Articles 71
Citations 1125
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Recent Articles
1.
Destache C, Isern R, Kenny D, El-Herte R, Plambeck R, Palmer C, et al.
Antibiotics (Basel) . 2024 Nov; 13(11). PMID: 39596718
ECMO is becoming widely used as a life-saving measure for critically ill patients. However, there is limited data on pharmacokinetics and the dosing of beta-lactam antibiotics in ECMO. In this...
2.
Jizba T, Ahmad F, Walters R, Foral P, Destache C, Velagapudi M
Proc (Bayl Univ Med Cent) . 2024 Jan; 37(1):127-134. PMID: 38174024
Background: Metronidazole treats obligate anaerobic bacterial and protozoal infections, with an elimination half-life of around 8 hours. The long elimination half-life, the favorable ratio of steady-state serum levels to minimum...
3.
Destache C, Boldt D, Anthone J, Velagapudi M, Swaney R, Jerabek J, et al.
Diagn Microbiol Infect Dis . 2023 Oct; 107(4):116085. PMID: 37801888
Background: We evaluated pre- and postimplementation of Virtuo on outcome in patients with gram-negative bacteremia using a quasiexperimental time-in-motion design. Methods: Becton Dickinson BACTEC™ 9000 series (Bactec) (2018) and Virtuo...
4.
Swaney R, Jokomo-Nyakabau R, Nguyen A, Kenny D, Millner P, Selim M, et al.
Microorganisms . 2023 Sep; 11(9). PMID: 37764170
The SARS-CoV-2 pandemic has resulted in a public health emergency with unique complications such as the development of fungal co-infections. The diagnosis of fungal infections can be challenging due to...
5.
Reiche W, Cooper S, Destache C, Sidhu S, Schutte B, Keirns D, et al.
Gastroenterology Res . 2023 Sep; 16(4):203-208. PMID: 37691752
Background: The management of patients with chronic hepatitis B (CHB) is complex and spans multiple medical specialties. As a result of this complexity, patients with CHB often do not receive...
6.
Bhattarai P, Hegde P, Li W, Prathipati P, Stevens C, Yang L, et al.
J Med Chem . 2022 Dec; 66(1):170-187. PMID: 36563291
Tuberculosis (TB), caused by (), is one of the leading causes of death in developing countries. Non-tuberculous mycobacteria (NTM) infections are rising and prey upon patients with structural lung diseases...
7.
Cooper S, Destache C, Vivekanandan R
Antimicrob Steward Healthc Epidemiol . 2022 Dec; 2(1):e142. PMID: 36483430
In this quality improvement project, we sought to increase the understanding and utilization of the antibiogram among physicians in family medicine, internal medicine, and surgery residency programs at a Midwest...
8.
Destache C, Ahmad F, Rajendrapasad S, Loranger A, Pruett W, Jagan N, et al.
Pharmacy (Basel) . 2022 Jul; 10(4). PMID: 35893707
Different pharmacotherapeutics have been introduced, and then stopped or continued, for the treatment of SARS-CoV-2. We evaluated the risks associated with mortality from SARS-CoV-2 infection. METHODS: Data was concurrently or...
9.
Mandal S, Sunagawa S, Prathipati P, Belshan M, Shibata A, Destache C
Nanomaterials (Basel) . 2022 Jun; 12(11). PMID: 35683795
The C-C motif chemokine receptor-5 (CCR5) expression on the T-cell surface is the prime barrier to HIV/AIDS eradication, as it promotes both active human immunodeficiency virus (HIV)-infection and latency; however,...
10.
Reid E, Walters R, Destache C
Antibiotics (Basel) . 2021 Dec; 10(12). PMID: 34943695
Introduction: (PA) is a leading cause of healthcare-associated infections. A variety of antibiotic classes are used in the treatment of PA infections, including beta-lactams (BLs) and fluoroquinolones (FQs), given either...