Christopher J Choi
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Explore the profile of Christopher J Choi including associated specialties, affiliations and a list of published articles.
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6
Citations
183
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Recent Articles
1.
Choi C, Rushton E, Vardy A, Higgins L, Augello A, Parod R
Toxicol Lett
. 2017 May;
276:138-143.
PMID: 28495613
In a National Toxicology Program (NTP) bioassay, inhalation of tetrahydrofuran (THF) induced liver tumors in female B6C3F mice but not in male mice or rats of either sex. Since THF...
2.
Choi C, Anantharam V, Martin D, Nicholson E, Richt J, Kanthasamy A, et al.
Toxicol Sci
. 2010 Feb;
115(2):535-46.
PMID: 20176619
Prion diseases are fatal neurodegenerative diseases resulting from misfolding of normal cellular prion (PrP(C)) into an abnormal form of scrapie prion (PrP(Sc)). The cellular mechanisms underlying the misfolding of PrP(C)...
3.
Anantharam V, Kanthasamy A, Choi C, Martin D, Latchoumycandane C, Richt J, et al.
Free Radic Biol Med
. 2008 Oct;
45(11):1530-41.
PMID: 18835352
Although the prion protein is abundantly expressed in the CNS, its biological functions remain unclear. To determine the endogenous function of the cellular prion protein (PrP(c)), we compared the effects...
4.
Choi C, Anantharam V, Saetveit N, Houk R, Kanthasamy A, Kanthasamy A
Toxicol Sci
. 2007 May;
98(2):495-509.
PMID: 17483122
The normal prion protein is abundantly expressed in the central nervous system, but its biological function remains unclear. The prion protein has octapeptide repeat regions that bind to several divalent...
5.
Choi C, Kanthasamy A, Anantharam V, Kanthasamy A
Neurotoxicology
. 2006 Jul;
27(5):777-87.
PMID: 16860868
Prion diseases are fatal neurodegenerative disorders that affect both humans and animals. The rapid clinical progression, change in protein conformation, cross-species transmission and massive neuronal degeneration are some key features...
6.
Kaul S, Anantharam V, Yang Y, Choi C, Kanthasamy A, Kanthasamy A
J Biol Chem
. 2005 Jun;
280(31):28721-30.
PMID: 15961393
Oxidative stress is a key apoptotic stimulus in neuronal cell death and has been implicated in the pathogenesis of many neurodegenerative disorders, including Parkinson disease (PD). Recently, we demonstrated that...