Christopher J Barbosa
Overview
Explore the profile of Christopher J Barbosa including associated specialties, affiliations and a list of published articles.
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5
Citations
270
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Recent Articles
1.
Semple S, Leone R, Barbosa C, Tam Y, Lin P
Pharmaceutics
. 2022 Feb;
14(2).
PMID: 35214130
The world raced to develop vaccines to protect against the rapid spread of SARS-CoV-2 infection upon the recognition of COVID-19 as a global pandemic. A broad spectrum of candidates was...
2.
Pardi N, LaBranche C, Ferrari G, Cain D, Tombacz I, Parks R, et al.
Mol Ther Nucleic Acids
. 2019 Apr;
15:36-47.
PMID: 30974332
Despite the enormous effort in the development of effective vaccines against HIV-1, no vaccine candidate has elicited broadly neutralizing antibodies in humans. Thus, generation of more effective anti-HIV vaccines is...
3.
Pardi N, Parkhouse K, Kirkpatrick E, McMahon M, Zost S, Mui B, et al.
Nat Commun
. 2018 Aug;
9(1):3361.
PMID: 30135514
Currently available influenza virus vaccines have inadequate effectiveness and are reformulated annually due to viral antigenic drift. Thus, development of a vaccine that confers long-term protective immunity against antigenically distant...
4.
Horsman G, Jirasek A, Vaillancourt F, Barbosa C, Jarzecki A, Xu C, et al.
J Am Chem Soc
. 2005 Dec;
127(48):16882-91.
PMID: 16316234
The basis of the respective regiospecificities of intradiol and extradiol dioxygenase is poorly understood and may be linked to the protonation state of the bidentate-bound catechol in the enzyme/substrate complex....
5.
Vaillancourt F, Barbosa C, Spiro T, Bolin J, Blades M, Turner R, et al.
J Am Chem Soc
. 2002 Mar;
124(11):2485-96.
PMID: 11890797
Ultraviolet resonance Raman spectroscopy (UVRRS), electronic absorption spectroscopy, and X-ray crystallography were used to probe the nature of the binding of 2,3-dihydroxybiphenyl (DHB) to the extradiol ring-cleavage enzyme, 2,3-dihydroxybiphenyl 1,2-dioxygenase...