Christopher Hug
Overview
Explore the profile of Christopher Hug including associated specialties, affiliations and a list of published articles.
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24
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1698
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Recent Articles
11.
Kasahara D, Williams A, Benedito L, Ranscht B, Kobzik L, Hug C, et al.
PLoS One
. 2013 Jun;
8(6):e65829.
PMID: 23755285
Adiponectin, an adipose derived hormone with pleiotropic functions, binds to several proteins, including T-cadherin. We have previously reported that adiponectin deficient (Adipo(-/-)) mice have increased IL-17A-dependent neutrophil accumulation in their...
12.
Williams A, Kasahara D, Verbout N, Fedulov A, Zhu M, Si H, et al.
PLoS One
. 2012 Jul;
7(7):e41088.
PMID: 22815927
Adiponectin is an adipose derived hormone that declines in obesity. We have previously shown that exogenous administration of adiponectin reduces allergic airways responses in mice. T-cadherin (T-cad; Cdh13) is a...
13.
Kasahara D, Kim H, Williams A, Verbout N, Tran J, Si H, et al.
J Immunol
. 2012 Apr;
188(9):4558-67.
PMID: 22474022
Pulmonary responses to ozone, a common air pollutant, are augmented in obese individuals. Adiponectin, an adipose-derived hormone that declines in obesity, has regulatory effects on the immune system. To determine...
14.
Zhu M, Hug C, Kasahara D, Johnston R, Williams A, Verbout N, et al.
Am J Respir Cell Mol Biol
. 2009 Nov;
43(4):487-97.
PMID: 19915153
Obese mice have increased responses to acute ozone (O(3)) exposure. T-cadherin is a binding protein for the high-molecular weight isoforms of adiponectin, an anti-inflammatory hormone that declines in obesity. The...
15.
Wong G, Krawczyk S, Kitidis-Mitrokostas C, Ge G, Spooner E, Hug C, et al.
FASEB J
. 2008 Sep;
23(1):241-58.
PMID: 18787108
Adiponectin is a major insulin-sensitizing, multimeric hormone derived from adipose tissue that acts on muscle and liver to regulate whole-body glucose and lipid metabolism. Here, we describe a novel and...
16.
Shore S, Terry R, Flynt L, Xu A, Hug C
J Allergy Clin Immunol
. 2006 Aug;
118(2):389-95.
PMID: 16890763
Background: Epidemiologic data indicate an increased incidence of asthma in the obese. Objective: Because serum levels of the insulin-sensitizing and anti-inflammatory adipokine adiponectin are reduced in obese individuals, we sought...
17.
Zhang C, Kaba M, Ge G, Xie K, Tong W, Hug C, et al.
Nat Med
. 2006 Jan;
12(2):240-5.
PMID: 16429146
Successful ex vivo expansion of hematopoietic stem cells (HSCs) would greatly benefit the treatment of disease and the understanding of crucial questions of stem cell biology. Here we show, using...
18.
Hug C, Lodish H
Curr Opin Pharmacol
. 2005 Mar;
5(2):129-34.
PMID: 15780820
Adiponectin, a novel hormone made by fat tissue, regulates energy metabolism and endothelial activation. Serum levels of adiponectin are reduced in conditions that are associated with an increased risk of...
19.
20.
Wong G, Wang J, Hug C, Tsao T, Lodish H
Proc Natl Acad Sci U S A
. 2004 Jul;
101(28):10302-7.
PMID: 15231994
Biochemical, genetic, and animal studies in recent years have established a critical role for the adipokine Acrp30/adiponectin in controlling whole-body metabolism, particularly by enhancing insulin sensitivity in muscle and liver,...