Christopher G Smith
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Explore the profile of Christopher G Smith including associated specialties, affiliations and a list of published articles.
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38
Citations
2393
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Recent Articles
1.
Rossi S, Dombrowe V, Godfrey L, Bucaciuc Mracica T, Pita S, Milne-Clark T, et al.
Oncogene
. 2025 Jan;
PMID: 39824946
Clear cell renal cell carcinoma (ccRCC) is characterised by significant genetic heterogeneity, which has diagnostic and prognostic implications. Very limited evidence is available regarding DNA methylation heterogeneity. We therefore generate...
2.
Embaby A, Huijberts S, Wang L, Leite de Oliveira R, Rosing H, Nuijen B, et al.
Clin Cancer Res
. 2024 May;
30(15):3157-3166.
PMID: 38739109
Purpose: The development of resistance limits the clinical benefit of BRAF and MEK inhibitors (BRAFi/MEKi) in BRAFV600-mutated melanoma. It has been shown that short-term treatment (14 days) with vorinostat was...
3.
Santonja A, Cooper W, Eldridge M, Edwards P, Morris J, Edwards A, et al.
EMBO Mol Med
. 2023 May;
15(6):e16505.
PMID: 37161793
Analysis of circulating tumor DNA (ctDNA) to monitor cancer dynamics and detect minimal residual disease has been an area of increasing interest. Multiple methods have been proposed but few studies...
4.
Rossi S, Newsham I, Pita S, Brennan K, Park G, Smith C, et al.
Sci Adv
. 2022 Sep;
8(39):eabn9828.
PMID: 36170366
Current gold standard diagnostic strategies are unable to accurately differentiate malignant from benign small renal masses preoperatively; consequently, 20% of patients undergo unnecessary surgery. Devising a more confident presurgical diagnosis...
5.
Stewart G, Welsh S, Ursprung S, Gallagher F, Jones J, Shields J, et al.
Br J Cancer
. 2022 Jun;
127(6):1051-1060.
PMID: 35739300
Background: Surgery for renal cell carcinoma (RCC) with venous tumour thrombus (VTT) extension into the renal vein (RV) and/or inferior vena cava (IVC) has high peri-surgical morbidity/mortality. NAXIVA assessed the...
6.
Markus H, Chandrananda D, Moore E, Mouliere F, Morris J, Brenton J, et al.
Sci Rep
. 2022 Feb;
12(1):1928.
PMID: 35121756
Circulating tumor DNA (ctDNA) in blood plasma is present at very low concentrations compared to cell-free DNA (cfDNA) of non-tumor origin. To enhance ctDNA detection, recent studies have been focused...
7.
Hudecova I, Smith C, Hansel-Hertsch R, Chilamakuri C, Morris J, Vijayaraghavan A, et al.
Genome Res
. 2021 Dec;
32(2):215-227.
PMID: 34930798
Current evidence suggests that plasma cell-free DNA (cfDNA) is fragmented around a mode of 166 bp. Data supporting this view has been mainly acquired through the analysis of double-stranded cfDNA....
8.
Mouliere F, Smith C, Heider K, Su J, van der Pol Y, Thompson M, et al.
EMBO Mol Med
. 2021 Jul;
13(8):e12881.
PMID: 34291583
Glioma-derived cell-free DNA (cfDNA) is challenging to detect using liquid biopsy because quantities in body fluids are low. We determined the glioma-derived DNA fraction in cerebrospinal fluid (CSF), plasma, and...
9.
Smith C, Cottrill H, Barton J
Am J Perinatol
. 2020 Aug;
39(3):265-271.
PMID: 32819018
Objective: This study aimed to describe a novel surgical technique for the management of antenatally suspected placenta accreta spectrum (PAS). Study Design: This is a retrospective, case series of patients...
10.
Smith C, Sharma D, Smith H, Zippay S, Bastin L, Acosta-Briceno L, et al.
Minerva Ginecol
. 2020 Jul;
72(6):430-435.
PMID: 32720803
No abstract available.